Two-point discrimination in diabetic patients

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dc.contributor.authorEryılmaz, Mehmet
dc.contributor.authorKoçer, Abdulkadir
dc.contributor.authorKocaman, Gülşen
dc.contributor.authorDikici, Süber
dc.date.accessioned2020-04-30T23:46:50Z
dc.date.available2020-04-30T23:46:50Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionKocer, Abdulkadir/0000-0003-2866-555Xen_US
dc.descriptionWOS: 000330123800011en_US
dc.descriptionPubMed: 23560652en_US
dc.description.abstractBackgroundDiabetes mellitus (DM) is a common cause of polyneuropathy. The aim of the present study was to evaluate two-point discrimination (TPD) compared with nerve conduction studies in the early stages of DM. MethodsForty-eight patients with early diagnosed (<5 years) type 2 DM and 17 healthy controls were evaluated. Of the patients with DM, 26 had neuropathic pain and 22 were asymptomatic. TPD and electrophysiological evaluations was obtained for all subjects. ResultsNerve conduction studies in patients showed findings related to both demyelination and axonal damage. Patients with neuropathic pain had higher TPD values on the plantar surface of the foot and both groups of DM patients had higher TPD values on the outer lateral malleolus compared with the control group (P < 0.05). There was a correlation between TPD and axonal damage in patients with neuropathic pain (P < 0.05). In patients without neuropathic pain, there was a correlation between TPD values and distal latencies of motor or sensory nerves (P < 0.05). In the control group, only third digit TPD values were related to the distal motor latency of the median nerve (P < 0.05). ConclusionIn conclusion, the TPD method is a less painful, practical, costeffective, and more easily applicable method that was completed in less timethan nerve conduction studies. Higher TPD values in the lower extremities indicate nerve damage in patients. These findings suggest that increased TPD values can easily determine neuropathy starting in the early stages of diabetes in patients with DM.en_US
dc.identifier.doi10.1111/1753-0407.12055en_US
dc.identifier.endpage448en_US
dc.identifier.issn1753-0393
dc.identifier.issn1753-0407
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage442en_US
dc.identifier.urihttps://doi.org/10.1111/1753-0407.12055
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5296
dc.identifier.volume5en_US
dc.identifier.wosWOS:000330123800011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Diabetesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdiabetes mellitusen_US
dc.subjectelectromyographyen_US
dc.subjectneuropathyen_US
dc.subjectsymptomsen_US
dc.subjecttwo-point discriminationen_US
dc.titleTwo-point discrimination in diabetic patientsen_US
dc.typeArticleen_US

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