Fluorescent CdTe/ZnS Core/Shell Quantum Dots for Sensitive Metabolite Detection in Real Samples

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dc.authoridDemirci, Tuna/0000-0001-8933-4944
dc.contributor.authorAgbulut, Melahat Sevgul Bakay
dc.contributor.authorElibol, Erdem
dc.contributor.authorCadirci, Musa
dc.contributor.authorDemirci, Tuna
dc.date.accessioned2025-10-11T20:48:45Z
dc.date.available2025-10-11T20:48:45Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractThis study highlights the aqueous synthesis of CdTe/ZnS core/shell quantum dots (QDs) and their application as fluorescence sensors for detecting critical metabolites, including folic acid, glucose, and vitamin C, in real biological samples. The synthesized QDs exhibit excellent quantum efficiency, stability, and biocompatibility, enhanced by mercaptopropionic acid (MPA) ligands, enabling eco-friendly and accurate sensing. Detection limits of 0.84 mu g/mL for folic acid, 0.33 mM for glucose, and 1.15 mu g/mL for vitamin C were achieved with high linearity (R-2 > 0.97). These results underscore the potential of CdTe/ZnS QDs in advanced biosensing technologies, offering sensitive and selective metabolite detection through a robust FRET-based mechanism. The versatility and aqueous solubility of these QDs pave the way for their integration into multiplex diagnostic systems for enhanced biomedical applications.en_US
dc.description.sponsorshipDuzce University [BAP-2022.06.03.1278]en_US
dc.description.sponsorshipDuzce University Scientific Research Projecten_US
dc.description.sponsorshipThis work was produced from the PhD Thesis Development of quantum dot-based fluorescence sensor for metabolite detection. This study was supported by Duzce University Scientific Research Project (BAP-2022.06.03.1278).en_US
dc.identifier.doi10.1007/s10895-025-04138-9
dc.identifier.issn1053-0509
dc.identifier.issn1573-4994
dc.identifier.pmid39833464en_US
dc.identifier.scopus2-s2.0-85217413481en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1007/s10895-025-04138-9
dc.identifier.urihttps://hdl.handle.net/20.500.12684/22076
dc.identifier.wosWOS:001401910300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer/Plenum Publishersen_US
dc.relation.ispartofJournal of Fluorescenceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectCdTe/ZnS QDsen_US
dc.subjectFluorescence detectionen_US
dc.subjectVitamin Cen_US
dc.subjectGlucoseen_US
dc.subjectFolic aciden_US
dc.titleFluorescent CdTe/ZnS Core/Shell Quantum Dots for Sensitive Metabolite Detection in Real Samplesen_US
dc.typeArticleen_US

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