Diabetes, Inflammatory Markers, and Tissue Thickness in Septic and Aseptic Hip Revision Surgeries

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dc.contributor.authorYucel, Mucahid Osman
dc.contributor.authorDalaslan, Rasit Emin
dc.contributor.authorSaglam, Sonmez
dc.contributor.authorArican, Mehmet
dc.contributor.authorKaraduman, Zekeriya Okan
dc.contributor.authorCelik, Mucahit
dc.contributor.authorKose, Mehmet Akif
dc.date.accessioned2025-10-11T20:48:01Z
dc.date.available2025-10-11T20:48:01Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground: Septic and aseptic loosening are the most common indications for revision hip arthroplasty (RHA), and infection-related revisions pose significant diagnostic and management challenges. This study compared septic and aseptic RHA cases in terms of inflammatory markers, prevalence of diabetes mellitus (DM), surgical time, blood transfusion requirements, soft-tissue thickness, and mortality rates in a cohort of 49 patients. Material/Methods: This retrospective study included 49 patients who underwent RHA between 2015 and 2020. Patients were divided into aseptic (n=34) and septic (n=15) groups. Demographic characteristics, comorbidities, preoperative erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels, soft-tissue thickness, and revision surgery time were compared. Results: ESR and CRP levels were significantly higher in the septic group (P=0.002, P=0.001), soft-tissue thickness was lower (p=0.003), blood transfusion requirements (P<0.001) and surgical times (P<0.00001) were higher, while no significant difference was found in mortality rates between the groups (P=0.576). Conclusions: This study examined septic and aseptic loosening in revision hip arthroplasty, finding higher inflammatory markers, increased transfusion needs, longer operative times, and greater infection risk with diabetes in septic cases. In our study, soft-tissue thickness was found to be lower in infected cases, unlike reports in the literature. While previous studies suggested that soft-tissue thickness was the cause of infection, our study indicates that the decrease in soft-tissue thickness is a consequence of infection.en_US
dc.identifier.doi10.12659/MSM.949619
dc.identifier.issn1643-3750
dc.identifier.pmid40859616en_US
dc.identifier.scopus2-s2.0-105015285977en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.12659/MSM.949619
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21711
dc.identifier.volume31en_US
dc.identifier.wosWOS:001560843800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Scientific Information, Incen_US
dc.relation.ispartofMedical Science Monitoren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectArthroplastyen_US
dc.subjectReplacementen_US
dc.subjectHipen_US
dc.subjectProsthesis Failureen_US
dc.subjectProsthesis-Related Infectionsen_US
dc.subjectReoperationen_US
dc.titleDiabetes, Inflammatory Markers, and Tissue Thickness in Septic and Aseptic Hip Revision Surgeriesen_US
dc.typeArticleen_US

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