The predictive effect of initial complete blood count of intensive care unit patients on mortality, length of hospitalization, and nosocomial infections

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dc.contributor.authorKutlucan, Leyla
dc.contributor.authorKutlucan, Ali
dc.contributor.authorBaşaran, Betül
dc.contributor.authorDağlı, Mehmet
dc.contributor.authorBaştürk, Abdulkadir
dc.contributor.authorKozanhan, Betül
dc.contributor.authorKöş, Mehmet
dc.date.accessioned2020-04-30T23:34:01Z
dc.date.available2020-04-30T23:34:01Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000380260000006en_US
dc.descriptionPubMed: 27160116en_US
dc.description.abstractOBJECTIVE: The mean platelet volume (MPV) can be used as an indicator of platelet activation. However, it has been shown that the platelet/lymphocyte ratio (PLR) can provide useful predictive information about inflammation and aggregation pathways. The neutrophil/lymphocyte ratio (NLR) may also be helpful as a marker of systemic or local inflammation. The main objective of this study evaluated to unselected critically ill patients the relationship of initial MPV, NLR, and PLR with mortality, length of hospitalization, and the risk of developing nosocomial infections in ICU patients. PATIENTS AND METHODS: In this retrospective study, we evaluated consecutive patients at our tertiary nine-bed ICU. One hundred seventy-three patients who were followed up during a 1-year period were included. RESULTS: MPV levels were found to be higher in patients who died in the hospital (p = 0.05). In addition, there was a significant positive correlation between expected mortality rate and MPV among non-survivors (p = 0.009). NLR levels were higher among non-survivors, but this difference was not statistically significant (p = 0.435). PLR levels were similar between non-survivors and survivors (p = 0.173). The initial NLR and PLR were significantly higher in patients with nosocomial infections. NLR and PLR had a significant positive correlation with length of hospitalization (p = 0.006 and p = 0.027, respectively). CONCLUSIONS: In our study, we found that high PLR and NLR may be indicators for the development of nosocomial infections. Moreover, the length of hospitalization may be prolonged in patients with high PLR and NLR.en_US
dc.identifier.endpage1473en_US
dc.identifier.issn1128-3602
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1467en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5089
dc.identifier.volume20en_US
dc.identifier.wosWOS:000380260000006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPlatelet/lymphocyte ratioen_US
dc.subjectNeutrophil/lymphocyte ratioen_US
dc.subjectMean platelet volumeen_US
dc.subjectPrognosisen_US
dc.subjectLength of hospitalizationen_US
dc.subjectNosocomial infectionsen_US
dc.titleThe predictive effect of initial complete blood count of intensive care unit patients on mortality, length of hospitalization, and nosocomial infectionsen_US
dc.typeArticleen_US

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