The effect of intermittent fasting and water restriction on myocardial ischemia/reperfusion-induced arrhythmia in rats

dc.contributor.authorKaya, Salih Tunç
dc.contributor.authorBozdoğan, Ömer
dc.date.accessioned2020-04-30T23:33:00Z
dc.date.available2020-04-30T23:33:00Z
dc.date.issued2012
dc.departmentDÜ, Fen-Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.descriptionWOS: 000321226500020en_US
dc.description.abstractAim: To investigate the effect of intermittent fasting and water restriction on ischemia/reperfusion-induced arrhythmias. Materials and methods: Six minutes of ischemia followed by 6 min of reperfusion was produced by the ligation and then releasing of the left coronary artery. Intermittent fasting and water restriction were applied during 1 month for 12 h/day. The duration, type, and incidence of arrhythmias during reperfusion and the survival rate at the end of reperfusion were determined and compared. Results: The score of arrhythmia that was determined using the type and duration of arrhythmia did not show significant differences among groups. The arrhythmic period was significantly longer in animals subjected to 1 month of intermittent water and food restriction. The risk of ischemic zone was found to be significantly larger in the animals subjected to 1 month of normal feeding after 1 month of food and water restriction. Conclusion: Intermittent fasting and water restriction was not found to be effective in decreasing the arrhythmia that occurred during 6 min of myocardial reperfusion in rats. Since there is no other study compatible with the present study, further research is required on the effect of intermittent fasting and water restriction on ischemia/reperfusion-induced arrhythmia and on the risk of an ischemic zone.en_US
dc.description.sponsorshipAbant Izzet Baysal University Research FundAbant Izzet Baysal University [2011.03.01.408]en_US
dc.description.sponsorshipWe thank the Abant Izzet Baysal University Research Fund for supporting this study (project number: 2011.03.01.408).en_US
dc.identifier.doi10.3906/sag-1204-83en_US
dc.identifier.endpage1489en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1484en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1204-83
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4871
dc.identifier.volume42en_US
dc.identifier.wosWOS:000321226500020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMyocardial ischemiaen_US
dc.subjectreperfusionen_US
dc.subjectfastingen_US
dc.subjectwater restrictionen_US
dc.subjectarrhythmiaen_US
dc.titleThe effect of intermittent fasting and water restriction on myocardial ischemia/reperfusion-induced arrhythmia in ratsen_US
dc.typeArticleen_US

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