Associations of alcohol consumption with blood pressure, lipoproteins, and subclinical inflammation among Turks

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dc.contributor.authorOnat, Altan
dc.contributor.authorHergenç, Gülay
dc.contributor.authorDursunoğlu, Dursun
dc.contributor.authorOrdu, Serkan
dc.contributor.authorCan, Günay
dc.contributor.authorBulur, Serkan
dc.contributor.authorYüksel, Hüsniye
dc.date.accessioned2020-04-30T22:39:56Z
dc.date.available2020-04-30T22:39:56Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000260292300007en_US
dc.descriptionPubMed: 18835594en_US
dc.description.abstractGender-related impact of alcohol consumption on blood pressure (BP), serum lipoprotein profile, and C-reactive protein (CRP) concentrations was evaluated prospectively. Alcohol drinking status was assessed as abstainers and categories of light, moderate, and heavy (daily >40 ml ethanol) intake. Mean age of the 3,443 men and women who were followed up for a mean of 7.4 years was 47.6 +/- 12 years. In each multivariable linear or logistic regression analysis, alcohol drinking status was adjusted for age, sex, smoking status, and physical activity. Among men. drinking was significantly associated positively with low-density lipo protein (LDL) cholesterol, apolipoprotein (apo) B, systolic and diastolic BR and with CRP in a log-linear manner exhibiting features of a threshold at heavy drinking. With respect to response of serum triglycerides to light-to-moderate drinking, whereas men exhibited a significant increase, women exhibited a decline (P < .05). Lower BPs (P < .03) and CRP levels (P = .032) were observed in female drinkers than abstainers and, as distinct from men, no increases in LDL cholesterol and apoB were noted. Heavy drinking tended to protect the sexes against the risk of developing low high-density lipoprotein cholesterol levels in prospective multi adjusted analyses. Sex modulates response of cardiometabolic risk variables to moderate alcohol consumption among Turks. Only women respond with lower triglycerides and CRP, whereas men show a log-linear positive association of drinking categories with BP, LDL cholesterol, apoB, and CRP. (C) 2008 Elsevier Inc. All rights reserved.en_US
dc.description.sponsorshipTurkish Society of Cardiology; PfizerPfizer; AstraZenecaAstraZeneca; SanofiAventisSanofi-Aventis; NovartisNovartis; Istanbulen_US
dc.description.sponsorshipWe thank the Turkish Society of Cardiology and the various pharmaceutical and nutritional companies (Pfizer, AstraZeneca, SanofiAventis, Novartis, Istanbul) that have financially supported the Turkish Adult Risk Factor surveys over the years. We appreciate the dedicated works of Z. Kucukdurmaz, MD, Z. Kaya, MD, M. Ugur, MD, and Mr. M. Ozmay, the co-workers in the survey teams.en_US
dc.identifier.doi10.1016/j.alcohol.2008.06.007en_US
dc.identifier.endpage601en_US
dc.identifier.issn0741-8329
dc.identifier.issn1873-6823
dc.identifier.issue7en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage593en_US
dc.identifier.urihttps://doi.org/10.1016/j.alcohol.2008.06.007
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2865
dc.identifier.volume42en_US
dc.identifier.wosWOS:000260292300007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofAlcoholen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlcohol consumptionen_US
dc.subjectApolipoprotein Ben_US
dc.subjectBlood pressureen_US
dc.subjectC-reactive proteinen_US
dc.subjectLDL cholesterolen_US
dc.subjectMetabolic syndromeen_US
dc.titleAssociations of alcohol consumption with blood pressure, lipoproteins, and subclinical inflammation among Turksen_US
dc.typeArticleen_US

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