Effect of potential risk factors on renal functions in simultaneous bilateral total knee arthroplasty

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dc.authoridUGUR, FATIH/0000-0001-6109-8425;
dc.contributor.authorAkar, Bedrettin
dc.contributor.authorUgur, Fatih
dc.contributor.authorYucel, Mucahid Osman
dc.contributor.authorAytug, Ferhan
dc.date.accessioned2025-10-11T20:47:49Z
dc.date.available2025-10-11T20:47:49Z
dc.date.issued2024
dc.departmentDüzce Üniversitesien_US
dc.description.abstractObjective This retrospective study investigated the risk factors leading to a decrease in Renal glomerular filtration rate (eGFR) and the development of acute kidney injury (AKI) during the early postoperative period in patients undergoing simultaneous bilateral total knee arthroplasty (SBTKA).Methods SBTKA was performed on 862 patients between 2014 and 2021 in a single center, by a single surgeon. The risk factors affecting the development of AKI were analyzed by monitoring the changes in pre-and postoperative serum creatinine (Scr) levels and eGFR values. RIFLE criteria were used to evaluate the kidney functions of the patients, who were followed up for an average of 6 months.Results While there was no decrease in eGFR or AKI in 818 patients postoperatively, eGFR decreased and AKI of different stages developed in 44 patients, according to the RIFLE criteria. Of the 44 patients with AKI, 31 had Risk, 9 had Injury, 3 had Failure, and one had Loss of kidney function. Two patients with American Society of Anaesthesiologists (ASA) class IV died due to deepening of postoperative renal dysfunction.Conclusion We found that the direct risk factors in SBTKA in terms of eGFR decrease and AKI development include long operation time, increased need for blood transfusion, and diabetic nephropathy, while increased body mass index (BMI) is an indirect risk factor. When planning for a SBTKA, we presume that a thorough analysis of these factors will decrease AKI risk.en_US
dc.identifier.doi10.3389/fsurg.2024.1405487
dc.identifier.issn2296-875X
dc.identifier.pmid39268493en_US
dc.identifier.scopus2-s2.0-85203817426en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3389/fsurg.2024.1405487
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21595
dc.identifier.volume11en_US
dc.identifier.wosWOS:001310250900001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherFrontiers Media Saen_US
dc.relation.ispartofFrontiers in Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjecttotal knee arthroplastyen_US
dc.subjectglomerular filtration rateen_US
dc.subjectacute kidney injuryen_US
dc.subjectpostoperative complicationen_US
dc.subjectosteoarthritisen_US
dc.subjectkneeen_US
dc.titleEffect of potential risk factors on renal functions in simultaneous bilateral total knee arthroplastyen_US
dc.typeArticleen_US

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