Evaluation of Risk Factors Determining Focal Organ Involvement in Patients Diagnosed with Brucellosis

dc.contributor.authorcakir-Kiymaz, Yasemin
dc.contributor.authorSungur, Mehmet Ali
dc.date.accessioned2025-10-11T20:47:40Z
dc.date.available2025-10-11T20:47:40Z
dc.date.issued2024
dc.departmentDüzce Üniversitesien_US
dc.description.abstractObjective: Brucellosis is a zoonotic infection that is common worldwide. It is a multisystemic disease in which specific organ involvement can be observed. However, no specific diagnostic tests can be used for early identification or prediction of focal organ involvement. This study aims to determine the risk factors that determine focal organ involvement in brucellosis. Methods: 143 patients who were followed with brucellosis between January and June 2022 were included in the study. The patients were divided into two groups, those with focal organ involvement and those without, and their clinical and laboratory findings were compared. The significance level was accepted as 0.05. Results: The average age of the patients was 45.64 +/- 17.3 years, and 51% (n=73) were women. The most common clinical findings were fatigue (97.2%, n=139), sweating (86.7%, n=124), and myalgia (68.5%, n=98). The most common form brucellosis was subacute brucellosis (52.4%, n=75). The focal organ involvement rate was 32.2% (n=46). The most common focal organ involvements were osteoarticular (27.9%, n=40), haematological (6.3%, n=9) and genitourinary (3.5%, n=5). There was no statistically significant difference between the groups in terms of age (p=0.698) and gender (p=0.374). While sweating was less in patients with focal brucellosis (p=0.010), back pain (p=0.046), hip pain (p <0.001), high ALT (p=0.014), high CRP (p=0.003) and high ESR (p <0.001) was more encountered. Conclusion: High CRP, ESR and ALT levels, anemia, back and hip pain may be parameters that predict focal organ involvement in patients diagnosed with brucellosis.en_US
dc.identifier.doi10.36519/kd.2024.4855
dc.identifier.endpage167en_US
dc.identifier.issn1301-143X
dc.identifier.issn1309-1484
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85205968428en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage161en_US
dc.identifier.trdizinid1282122en_US
dc.identifier.urihttps://doi.org/10.36519/kd.2024.4855
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1282122
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21521
dc.identifier.volume37en_US
dc.identifier.wosWOS:001343256300003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherDoc Design Informatics Co Ltden_US
dc.relation.ispartofKlimik Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectbrucellaen_US
dc.subjectfocal infectionen_US
dc.subjectrisk factorsen_US
dc.titleEvaluation of Risk Factors Determining Focal Organ Involvement in Patients Diagnosed with Brucellosisen_US
dc.typeArticleen_US

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