Is the ABO Blood Group a Predictor of Renal Allograft Survival in ABO Identical Donor Recipients?

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dc.authorid
dc.contributor.authorBoran, Ertay
dc.contributor.authorBoran, Mediha
dc.date.accessioned2021-12-01T18:23:05Z
dc.date.available2021-12-01T18:23:05Z
dc.date.issued2021
dc.department[Belirlenecek]en_US
dc.description.abstractObjective: The effect of the ABO blood group on renal allograft survival (AS) is unclear. We assessed the influence of theABO blood group on AS and performed a comparative analysis of AS in kidney transplant recipients with different ABOblood groups.Methods: The 239 renal transplant recipients who underwent transplantation in a single center were stratified into the3 groups: blood group O (84, 35.14%), blood group A (104, 43.51%), and due to the low number of blood group AB patients,blood groups B and AB were classified as blood group B (51, 21.3%). Clinical outcomes and patient demographics wereinvestigated and compared between groups.Results: The AS of blood group O recipients was significantly longer than that of blood group B recipients (P = .001).Correlation analyses revealed that recipient age (P = .002), donor age (P = .013), creatinine level (P = .022), estimated glomerular filtration rate (eGFR) (P = .005), human leukocyte antigen (HLA) mismatches (P = .001), blood group O (P < .0001),blood group B (P < .0001), cyclosporine A (P < .0001), and sirolimus treatment (P = .032) were predictors of AS. Multivariateregression analyses indicated that blood group B (? = ?0.618, P < .0001) and cyclosporine A-based immunosuppression (?= ?0.924, P < .0001) were negative predictors of AS.Conclusion: The data presented here showed that eGFR, low recipient age, low donor age, patient gender (male), and3 HLA mismatches were correlated with long-term AS. In contrast, shorter AS was associated with the blood group B andcyclosporine A treatment.en_US
dc.identifier.doi10.5152/turkjnephrol.2021.4737
dc.identifier.endpage217en_US
dc.identifier.issn1300-7718
dc.identifier.issn2667-4440
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85112115081en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage213en_US
dc.identifier.urihttps://doi.org/10.5152/turkjnephrol.2021.4737
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TkRVMU5EUXpNdz09
dc.identifier.urihttps://hdl.handle.net/20.500.12684/9634
dc.identifier.volume30en_US
dc.identifier.wosWOS:000681656200004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish journal of nephrology (Online)en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keywords]en_US
dc.titleIs the ABO Blood Group a Predictor of Renal Allograft Survival in ABO Identical Donor Recipients?en_US
dc.typeArticleen_US

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