Cerebral Venous Sinus Thrombosis in Women: Subgroup Analysis of the VENOST Study

dc.authoridkarahan, ali yavuz/0000-0001-8142-913X
dc.authoridYesilot, Nilufer/0000-0002-9655-9487
dc.authoridSahin, Sevki/0000-0003-2016-9965
dc.authoridGOKSEL, BASAK KARAKURUM/0000-0003-2766-2277
dc.authoridYesilot, Nilufer/0000-0002-9655-9487
dc.authoridBatur Caglayan, Hale/0000-0002-3279-1842
dc.authoridUZUNER, NEVZAT/0000-0002-4961-4332
dc.authorwosidkarahan, ali yavuz/E-4481-2017
dc.authorwosidYesilot, Nilufer/A-6597-2013
dc.authorwosidSahin, Sevki/Q-1134-2019
dc.authorwosidGOKSEL, BASAK KARAKURUM/AAE-2609-2021
dc.authorwosidNazliel, Bijen/ABI-2924-2020
dc.authorwosidYesilot, Nilufer/AAB-9058-2021
dc.authorwosidBatur Caglayan, Hale/AAZ-6048-2021
dc.contributor.authorUluduz, Derya
dc.contributor.authorSahin, Sevki
dc.contributor.authorDuman, Taskin
dc.contributor.authorOzturk, Serefnur
dc.contributor.authorYayla, Vildan
dc.contributor.authorAfsar, Nazire
dc.contributor.authorInce, Birsen
dc.date.accessioned2021-12-01T18:51:19Z
dc.date.available2021-12-01T18:51:19Z
dc.date.issued2020
dc.department[Belirlenecek]en_US
dc.description.abstractBackground. Early diagnosis of cerebral venous sinus thrombosis (CVST) associated with reproductive health-related risk factors (RHRF) including pregnancy, puerperium, and oral contraceptive (OC) use can prevent severe neurological sequelae; thus, the symptoms must be documented in detail for each group.Methods. Out of 1144 patients with CVST, a total of 777 women were enrolled from a multicenter for the study of cerebral venous sinus thrombosis (VENOST). Demographic, biochemical, clinical, and radiological aspects were compared for 324 cases with RHRF and 453 cases without RHRF.Results. The mean age of the RHRF (-) group (43.2 +/- 13 years) was significantly higher than of the RHRF (+) group (34 +/- 9years). A previous history of deep venous thrombosis (3%), isolated cavernous sinus involvement (1%), cranial neuropathy (13%), comorbid malignancy (7%), and its disability scores after 12 months (9%) were significantly higher in the RHRF (-) group. The RHRF (+) group consisted of 44% cases of puerperium, 33% cases of OC users and 23% of pregnant women. The mean age was found to be higher in OC users (38 +/- 9years). A previous history of deep venous thrombosis was slightly higher in the pregnancy subgroup (4%). Epileptic seizures were more common in the puerperium group (44%).Conclusion. The results of our study indicate that the risk of CSVT increases parallel to age, OC use, and puerperium period. In addition, when considering the frequency of findings and symptoms, epileptic seizures in the puerperium subgroup of the RHRF (+) group and malignancies in the RHRF (-) group may accompany the CSVT. In daily practice, predicting these risks for the CSVT and early recognition of the symptoms will provide significant benefits to patients.en_US
dc.identifier.doi10.1155/2020/8610903
dc.identifier.issn2090-8105
dc.identifier.issn2042-0056
dc.identifier.pmid32953038en_US
dc.identifier.scopus2-s2.0-85091439977en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1155/2020/8610903
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10993
dc.identifier.volume2020en_US
dc.identifier.wosWOS:000570429300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofStroke Research And Treatmenten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPostpartum Perioden_US
dc.subjectPregnancyen_US
dc.subjectRisken_US
dc.subjectThromboembolismen_US
dc.subjectStrokeen_US
dc.subjectPuerperiumen_US
dc.subjectVeinen_US
dc.titleCerebral Venous Sinus Thrombosis in Women: Subgroup Analysis of the VENOST Studyen_US
dc.typeArticleen_US

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