Evaluation of parenchymal collaterals in patients with meningioma using contrast-enhanced T1 MPRAGE sequence

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dc.authoridOgul, Hayri/0000-0001-5989-3729;
dc.contributor.authorGozgec, Elif
dc.contributor.authorOgul, Hayri
dc.contributor.authorNaldemir, Ibrahim Feyyaz
dc.contributor.authorSakci, Zakir
dc.contributor.authorKantarci, Mecit
dc.date.accessioned2025-10-11T20:48:28Z
dc.date.available2025-10-11T20:48:28Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground: Post-contrast T1-MPRAGE sequence has been used in routine tumor imaging at many centers for decades. Meningiomas may be accompanied by leptomeningeal as well as parenchymal collaterals. In this study, we aimed to demonstrate the collaterals that may accompany meningiomas on postcontrast T1-MPRAGE imaging and to investigate their relationship with location, size, histologic features, adjacent bone, and parenchymal changes. Methods: In this study, postcontrast T1-MPRAGE images of 326 meningiomas from 259 patients were independently analyzed by two observers. The presence of parenchymal collaterals and unilateral, contralateral or bilateral localization were determined. Meningiomas' diameters, locations, presence of dural sinus invasion, associated parenchymal changes and bony changes were determined. Histologic grades were determined if applicable. The data obtained were analyzed statistically. Results: Parenchymal collaterals were demonstrated in 25% of meningiomas (66/259). Of these, 65% were unilateral, 12% contralateral and 23% bilateral. There was a significant correlation between malignancy and the presence of collaterals in histologically diagnosed meningiomas (77%, p = 0.01). The presence of collaterals was also significantly higher in meningiomas with sinus invasion and bone destruction (p < 0.001). As tumor size increased, unilateral and bilateral collateral development increased (p < 0.001, p = 0.008, respectively), but it was not significant in contralateral cases. There was significant concordance between the observers in terms of the presence of collaterals (kappa: 0.773). Conclusions: Meningiomas may be accompanied by parenchymal collaterals. WHO grade 3 histologic type, sinus invasion, bone destruction and size increase are predictors of collateral development.en_US
dc.identifier.doi10.1016/j.neuchi.2025.101664
dc.identifier.issn0028-3770
dc.identifier.issn1773-0619
dc.identifier.issue3en_US
dc.identifier.pmid40157601en_US
dc.identifier.scopus2-s2.0-105000864313en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.neuchi.2025.101664
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21940
dc.identifier.volume71en_US
dc.identifier.wosWOS:001461805600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMasson Editeuren_US
dc.relation.ispartofNeurochirurgieen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectMeningiomaen_US
dc.subjectParenchymal collateralen_US
dc.subjectT1 MPRAGEen_US
dc.titleEvaluation of parenchymal collaterals in patients with meningioma using contrast-enhanced T1 MPRAGE sequenceen_US
dc.typeArticleen_US

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