Biomonitoring of bisphenol A, 4-nonylphenol, and 4-t-octylphenol in Turkish population: exposure and risk assessment

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dc.authoridÜnlüsayın, İrfan/0000-0002-1610-1952
dc.authoridKocadal, Kumsal/0000-0002-6156-4139
dc.authoridCOK, ISMET/0000-0003-3128-677X
dc.authoridBattal, Dilek/0000-0003-1935-5330
dc.authorwosidCOK, ISMET/AAJ-6980-2021
dc.contributor.authorŞüküroğlu, Ayça Aktaş
dc.contributor.authorBattal, Dilek
dc.contributor.authorKocadal, Kumsal
dc.contributor.authorSungur, Mehmet Ali
dc.contributor.authorÇok, İsmet
dc.contributor.authorÜnlüsayın, İrfan
dc.date.accessioned2023-07-26T11:51:30Z
dc.date.available2023-07-26T11:51:30Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractBiomonitoring studies are important tools to understand the effects of endocrine-disrupting compounds on human health. Up to now, there have been no biomonitoring and risk assessment studies conducted in Turkish population in which urinary bisphenol A (BPA), 4-nonylphenol (4-NP), and 4-t-octylphenol (4-t-OP) levels were measured simultaneously. The aim of this study is to measure urinary BPA, 4-NP, and 4-t-OP on Turkish population and conduct a risk assessment using urinary levels of chemicals of interest. During the study, liquid chromatography with tandem mass spectrometry (LC-MS/MS) was used to measure urinary levels of above-mentioned chemicals, and human biomonitoring was used as a risk assessment tool in 103 volunteers, living in Mersin Region, Turkey. Urinary BPA, 4-NP, and 4-t-OP were founded as 0.0079 mu g/g creatinine, 0.0177 mu g/g creatinine, and 0.0114 mu g/g creatinine, respectively. The obtained estimated daily intakes (EDIs) were calculated as 0.095 mu g/kg bw/day, 0.041 mu g/kg bw/day, and 0.091 mu g/kg bw/day, for BPA, 4-NP, and 4-t-OP, respectively. In conclusion, although no potential health risk due to BPA and 4-NP exposure was observed, there might be health risks associated with 4-t-OP exposure in the Turkish population.en_US
dc.description.sponsorshipMersin University, Department of Scientific Research Projects [BAP-ECZ F EMBB (DB) 2012-8 A]en_US
dc.description.sponsorshipThis work was supported by the Mersin University, Department of Scientific Research Projects [Grant Number: BAP-ECZ F EMBB (DB) 2012-8 A].en_US
dc.identifier.doi10.1007/s11356-021-17796-6
dc.identifier.endpage26262en_US
dc.identifier.issn0944-1344
dc.identifier.issn1614-7499
dc.identifier.issue18en_US
dc.identifier.pmid34850348en_US
dc.identifier.scopus2-s2.0-85120324259en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage26250en_US
dc.identifier.urihttps://doi.org/10.1007/s11356-021-17796-6
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12573
dc.identifier.volume29en_US
dc.identifier.wosWOS:000724093600005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSungur, Mehmet Ali
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofEnvironmental Science and Pollution Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectBiomonitoring; Endocrine-Disrupting Chemical; Bisphenol A; 4-T-Octylphenol; 4-Nonylphenol; Turkish Populationen_US
dc.subjectEndocrine-Disrupting Compounds; Solid-Phase Extraction; Human Urine; Alkylphenol Ethoxylates; Nonylphenol; Metabolites; Fate; Octylphenol; Water; Bioconcentrationen_US
dc.titleBiomonitoring of bisphenol A, 4-nonylphenol, and 4-t-octylphenol in Turkish population: exposure and risk assessmenten_US
dc.typeArticleen_US

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