The Antibacterial and Antifungal Activity of Chlorhexidine Diacetate Incorporated into Acrylic Resins Used in Provisional Restorations

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dc.authorscopusid58254536300en_US
dc.authorscopusid56526673700en_US
dc.authorscopusid34880569600en_US
dc.authorscopusid56049522100en_US
dc.contributor.authorAta, Secil Ozkan
dc.contributor.authorAkay, Canan
dc.contributor.authorMumcu, Emre
dc.contributor.authorErdonmez, Demet
dc.date.accessioned2024-08-23T16:03:56Z
dc.date.available2024-08-23T16:03:56Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractObjective: The surface of provisional restorations applied before conventional or implant-supported fixed restorations may cause bacterial or fungal biofilm formation. The aim of this study was to evalu-ate the antimicrobial activity of acrylic resins used in provisional restorations modified with chlorhex-idine diacetate. Methods: 120 cylindrical, auto-polymerized resin samples modified with chlorhexi-dine diacetate were prepared at concentrations of 0 (control), 1, 3, 5 wt %. The antimicrobial activity was examined against Streptococcus mutans, Enterococcus faecalis, and Candida albicans using Crystal Violet quantification, MTT assay, and Scanning Electron Microscopy. Data were analyzed by ANOVA and paired sample t-tests (alpha=0.05). Results: The addition of chlorhexidine diacetate influ-enced the growth rate and metabolic activity of microorganisms. The antimicrobial effect against C. albicans and S. mutans statistically increased with the percentage of chlorhexidine diacetate. E. fae- calis bacteria were less affected by chlorhexidine diacetate compared to other pathogens. Conclu-sion: It has been shown that the effectiveness of CHDA in inhibiting the proliferation of microorgan-isms correlated positively with increasing concentration levels. More research is needed to confirm the impact of different chlorhexidine concentrations on the mechanical properties, clinical efficacy, and antimicrobial properties of CDHA.en_US
dc.identifier.doi10.15644/asc57/3/4
dc.identifier.endpage247en_US
dc.identifier.issn0001-7019
dc.identifier.issn1846-0410
dc.identifier.issue3en_US
dc.identifier.pmid37808409en_US
dc.identifier.scopus2-s2.0-85172931493en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage238en_US
dc.identifier.urihttps://doi.org/10.15644/asc57/3/4
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13991
dc.identifier.volume57en_US
dc.identifier.wosWOS:001083055300004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherUniv Zagreb, Sch Dental Medicineen_US
dc.relation.ispartofActa Stomatologica Croaticaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectProvisional Restorationsen_US
dc.subjectProsthodonticsen_US
dc.subjectAntimicrobial Effecten_US
dc.subjectBiofilm Formationen_US
dc.subjectCandida-Albicansen_US
dc.subjectCompositesen_US
dc.subjectReleaseen_US
dc.subjectMutansen_US
dc.subjectModelen_US
dc.titleThe Antibacterial and Antifungal Activity of Chlorhexidine Diacetate Incorporated into Acrylic Resins Used in Provisional Restorationsen_US
dc.typeArticleen_US

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