Retinal and Choroidal Thickness in Patients with High Myopia without Maculopathy

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dc.contributor.authorTeberik, Kuddusi
dc.contributor.authorKaya, Murat
dc.date.accessioned2020-04-30T23:31:41Z
dc.date.available2020-04-30T23:31:41Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000422798200028en_US
dc.descriptionPubMed: 29492074en_US
dc.description.abstractObjective: To evaluate macular choroidal thickness (CT) and retinal thickness in Turkish patients with high myopia without maculopathy and in normal subjects and to examine the association with age, axial length (AL), best corrected visual acuity (BCVA), cycloplegic refraction, and spherical equivalent (SE). Methods: This prospective study was performed between January 2015 and June 2016 in the Department of Ophthalmology, Duzce University Medical Faculty. It had 65 individuals (30 patients with high myopia, 35 healthy subjects). Retinal and choroidal images were obtained using spectral-domain optical coherence tomography (OCT). Measurements (one subfoveal, three temporal, three nasal) were taken at 500 mu m intervals up to 1,500 mu m using the caliper system. Only the right eye was used for subsequent analysis. Results: The mean age was 29.5 +/- 14.5 years and 25.6 +/- 7.0 in the high myopia and control groups, respectively. The subfoveal CT was significantly lower in the high myopia group (mean, 218.3 +/- 102.25 mm) than the control group (mean, 331.83 +/- 99.06 mm; p < 0.001). In both groups, the choroid was thinnest at the nasal 1,500 mu m location, being 158.40 +/- 90.8 mu m and 301 +/- 103.59 mu m, respectively. Retinal thickness in both groups was thickest at the nasal 1,500 mu m location and thinnest in the subfoveal region. In patients with high myopia, CT was negatively correlated with AL (r=-0.490, p=0.006) and age (r=-0.455, p=0.012). Conclusions: Highly myopic eyes have a thinner choroid, which may be secondary to longer AL but is not an independent factor. Further studies in the field of OCT are important to exploring the pathology of high myopia.en_US
dc.description.sponsorshipDuzce University Research FundDuzce University [2014.04.02.284]en_US
dc.description.sponsorshipThis project was supported by Duzce University Research Fund Project Number: 2014.04.02.284en_US
dc.identifier.doi10.12669/pjms.336.13726en_US
dc.identifier.endpage1443en_US
dc.identifier.issn1682-024X
dc.identifier.issue6en_US
dc.identifier.startpage1438en_US
dc.identifier.urihttps://doi.org/10.12669/pjms.336.13726
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4411
dc.identifier.volume33en_US
dc.identifier.wosWOS:000422798200028en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherProfessional Medical Publicationsen_US
dc.relation.ispartofPakistan Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAxial lengthen_US
dc.subjectChoroidal thicknessen_US
dc.subjectHigh myopiaen_US
dc.subjectRetinal thicknessen_US
dc.subjectSpectral-domain optical coherence tomographyen_US
dc.titleRetinal and Choroidal Thickness in Patients with High Myopia without Maculopathyen_US
dc.typeArticleen_US

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