Development of a cream formulation containing bee venom and other bee products

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dc.contributor.authorSamancı, Aslı Elif Tanuğur
dc.contributor.authorKekeçoğlu, Meral
dc.date.accessioned2023-07-26T11:58:28Z
dc.date.available2023-07-26T11:58:28Z
dc.date.issued2022
dc.departmentDÜ, Fen-Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractThis study aimed to develop a prototype skincare product with bee venom, propolis, honey, beeswax, and royal jelly. The prototype formulation contained 0.1% bee venom, 0.3% propolis extract, 0.45% honey, and 1.0% royal jelly. The prototype body cream was analyzed for stability, antioxidant activity, dermatological response, and cytotoxicity. In addition, a panel test evaluated the prototype for the claims such as skin smoothness, feelings of nourishment, moisturizing, skin tone, brightness, and visibility of wrinkles. According to the stability test, the prototype was stable for up to 90 days at room temperature and +40 degrees C. The formulation was found to have a high antioxidant capacity at 85.45%. Cell viability detected over 70% indicated that the prototype body cream was not cytotoxic. The dermatological analysis revealed no irritation or allergic reaction in non-allergic individuals. Panel test showed that the prototype makes skin silky smooth, contributes to hydration, brightens and nourishes the skin, evens the skin tone, reduces the visibility of wrinkles, improves skin elasticity, and smoothes wrinkles. This prototype formulation requires further research to evaluate its effectiveness against skin aging on different skin types. Nevertheless, the side effects of such products need particular attention in developing a commercial product containing bee venom in susceptible individuals.en_US
dc.description.sponsorshipSBS Bilimsel BioCozumler RD Centeren_US
dc.description.sponsorshipSBS Bilimsel BioCozumler R&D Centeren_US
dc.identifier.doi10.1111/jocd.14891
dc.identifier.endpage4920en_US
dc.identifier.issn1473-2130
dc.identifier.issn1473-2165
dc.identifier.issue10en_US
dc.identifier.pmid35238152en_US
dc.identifier.scopus2-s2.0-85128660652en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage4913en_US
dc.identifier.urihttps://doi.org/10.1111/jocd.14891
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13497
dc.identifier.volume21en_US
dc.identifier.wosWOS:000786415600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSamancı, Aslı Elif Tanuğur
dc.institutionauthorKekeçoğlu, Meral
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Cosmetic Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectAntiaging; Bee Venom; Body Cream; Propolis; Royal Jellyen_US
dc.subjectSkin; Propolis; Protectsen_US
dc.titleDevelopment of a cream formulation containing bee venom and other bee productsen_US
dc.typeArticleen_US

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