Detection of atrial electromechanical dysfunction in obesity

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dc.contributor.authorErdem, Fatma Hızal
dc.contributor.authorÖztürk, Serkan
dc.contributor.authorBaltacı, Davut
dc.contributor.authorDönmez, İbrahim
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorAyhan, Selim
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2020-05-01T09:11:19Z
dc.date.available2020-05-01T09:11:19Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAlcelik, Aytekin/0000-0002-3156-1076en_US
dc.descriptionWOS: 000367502600008en_US
dc.descriptionPubMed: 26717216en_US
dc.description.abstractIntroduction Obesity is associated with atrial fibrillation and is known as an independent risk factor. The aim of our study was to investigate if there was any association between the body mass index and atrial electromechanical intervals in obese and non-obese patients. Methods Seventy patients were enrolled in the study. Body mass index (BMI), functional capacity, and fasting blood sugar were evaluated; then, these patients were divided into two groups, patients who had a BMI >= 30 were known as obese (35 patients) and those who had a BMI <30 were known as non-obese patients. All patients were evaluated by transthoracic echocardiography. LA volumes were measured by the discs method in the apical four-chamber view. LA active and passive emptying volumes and fraction were calculated. Using TDI, atrial electromechanical coupling (PA) was measured from the lateral mitral annulus (PA lateral), septal mitral annulus (PA septum), and right ventricular tricuspid annulus (PA tricuspid). Results LA diameter was significantly higher in obese patients (P=0.021). LA passive emptying volume and fraction were significantly decreased in obese patients (P = 0.038 and P = 0.011). LA active emptying volume and fraction were significantly increased in obese patients (P = 0.001 and P = 0.001). Left intraatrial and interatrial electromechanical delay were significantly higher in obese patients (18.9 +/- 3.8 vs 11.9 +/- 2.0, P < 0.001 and 29.5 +/- 4.1 vs 17.9 +/- 2.5, P < 0.001). Also interatrial electromechanical delay correlated positively with BMI. Conclusion This study revealed that delayed atrial electromechanical interval and impaired LA mechanical functions were related to BMI in obese patients. These findings may be an early sign of subclinical atrial dysfunction and arrhythmias in obese patients.en_US
dc.identifier.doi10.2143/AC.70.6.3120180en_US
dc.identifier.endpage684en_US
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage678en_US
dc.identifier.urihttps://doi.org/10.2143/AC.70.6.3120180
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5501
dc.identifier.volume70en_US
dc.identifier.wosWOS:000367502600008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObesityen_US
dc.subjectbody mass indexen_US
dc.subjectatrial functionen_US
dc.titleDetection of atrial electromechanical dysfunction in obesityen_US
dc.typeArticleen_US

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