Hybrid biomanufacturing systems applied in tissue regeneration

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dc.authoridAslan, Enes/0000-0002-1849-2715en_US
dc.authoridLiu, Fengyuan/0000-0002-7915-5341en_US
dc.authorscopusid57195738146en_US
dc.authorscopusid58573417600en_US
dc.authorscopusid57193900687en_US
dc.authorscopusid57216299590en_US
dc.authorwosidAslan, Enes/JAN-4557-2023en_US
dc.contributor.authorLiu, Fengyuan
dc.contributor.authorQuan, Rixiang
dc.contributor.authorVyas, Cian
dc.contributor.authorAslan, Enes
dc.date.accessioned2024-08-23T16:03:52Z
dc.date.available2024-08-23T16:03:52Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractScaffold-based approach is a developed strategy in biomanufacturing, which is based on the use of temporary scaffold that performs as a house of implanted cells for their attachment, proliferation, and differentiation. This strategy strongly depends on both materials and manufacturing processes. However, it is very difficult to meet all the requirements, such as biocompatibility, biodegradability, mechanical strength, and promotion of cell-adhesion, using only single material. At present, no single bioprinting technique can meet the requirements for tissue regeneration of all scales. Thus, multi-material and mixing-material scaffolds have been widely investigated. Challenges in terms of resolution, uniform cell distribution, and tissue formation are still the obstacles in the development of bioprinting technique. Hybrid bioprinting techniques have been developed to print scaffolds with improved properties in both mechanical and biological aspects for broad biomedical engineering applications. In this review, we introduce the basic multi-head bioprinters, semi-hybrid and fully-hybrid biomanufacturing systems, highlighting the modifications, the improved properties and the effect on the complex tissue regeneration applications.en_US
dc.identifier.doi10.18063/ijb.v9i1.646
dc.identifier.endpage335en_US
dc.identifier.issn2424-7723
dc.identifier.issn2424-8002
dc.identifier.issue1en_US
dc.identifier.pmid36636138en_US
dc.identifier.scopus2-s2.0-85150017997en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage320en_US
dc.identifier.urihttps://doi.org/10.18063/ijb.v9i1.646
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13957
dc.identifier.volume9en_US
dc.identifier.wosWOS:000928284900002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWhioce Publ Pte Ltden_US
dc.relation.ispartofInternational Journal of Bioprintingen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdditive biomanufacturingen_US
dc.subjectHybrid bioprinteren_US
dc.subjectTissue regenerationen_US
dc.subjectScaffoldsen_US
dc.subjectScaffoldsen_US
dc.subjectBiomaterialsen_US
dc.subjectFabricationen_US
dc.subjectConstructsen_US
dc.subjectHydrogelen_US
dc.subjectPlasmaen_US
dc.subjectMultien_US
dc.titleHybrid biomanufacturing systems applied in tissue regenerationen_US
dc.typeReviewen_US

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