Minimally Invasive Treatment of Giant Haemangiomas of the Liver: Embolisation With Bleomycin

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dc.contributor.authorBozkaya, Halil
dc.contributor.authorÇınar, Celal
dc.contributor.authorBeşir, Fahri Halit
dc.contributor.authorParıldar, Mustafa
dc.contributor.authorOran, İsmail
dc.date.accessioned2020-04-30T23:19:14Z
dc.date.available2020-04-30T23:19:14Z
dc.date.issued2014
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000329994100012en_US
dc.descriptionPubMed: 23580121en_US
dc.description.abstractThe management of patients with giant haemangioma of the liver remains controversial. Although the usual treatment method for symptomatic giant haemangioma is surgery, the classical paradigm of operative resection remains. In this study, we evaluated the symptomatic improvement and size-reduction effect of embolisation with bleomycin mixed with lipiodol for the treatment of symptomatic giant hepatic haemangioma. This study included 26 patients [21 female, five male; age 41-65 years (mean 49.83 +/- A 1.53)] with symptomatic giant haemangioma unfit for surgery and treated with selective embolisation by bleomycin mixed with lipiodol. The patients were followed-up (mean 7.4 +/- A 0.81 months) clinically and using imaging methods. Statistical analysis was performed using SPSS version 16.0, and p < 0.05 was considered to indicate statistical significance. Embolisation of 32 lesions in 26 patients was performed. The mean volume of the haemangiomas was 446.28 +/- A 88 cm(3) (range 3.39-1559 cm(3)) before intervention and 244.43 +/- A 54.38 cm(3) (range 94-967 cm(3)) after intervention. No mortality or morbidity related to the treatment was identified. Symptomatic improvement was observed in all patients, and significant volume reduction was achieved (p = 0.001). The morbidity of surgical treatment in patients with giant liver hemangioma were similar to those obtained in patients followed-up without treatment. Therefore, follow-up without treatment is preferred in most patients. Thus, minimally invasive embolisation is an alternative and effective treatment for giant symptomatic haemangioma of the liver.en_US
dc.identifier.doi10.1007/s00270-013-0618-yen_US
dc.identifier.endpage107en_US
dc.identifier.issn0174-1551
dc.identifier.issn1432-086X
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage101en_US
dc.identifier.urihttps://doi.org/10.1007/s00270-013-0618-y
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3694
dc.identifier.volume37en_US
dc.identifier.wosWOS:000329994100012en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofCardiovascular And Interventional Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCavernous haemangiomaen_US
dc.subjectLiver neoplasmen_US
dc.subjectTherapeutic embolisationen_US
dc.subjectIodized oilen_US
dc.subjectBleomycinen_US
dc.titleMinimally Invasive Treatment of Giant Haemangiomas of the Liver: Embolisation With Bleomycinen_US
dc.typeArticleen_US

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