Long-acting risperidone: a review of its role in the treatment of bipolar disorder

Yükleniyor...
Küçük Resim

Tarih

2009

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Bipolar disorder is a multidimensional illness typified by fluctuating periods of depression and mania, cognitive dysfunction, abnormal circadian rhythms, and multiple comorbid psychiatric and general medical conditions. Indefinite pharmacological treatment is often required, yet the modest effects of available treatments and frequent difficulties with tolerability and adherence present complex challenges to patients. Long-acting injectable medications offer a therapeutic alternative to oral mood stabilizers and may help facilitate long-term treatment adherence. This article will provide a succinct review of the latest data on the use of long-acting injectable risperidone (LAR) during the maintenance-phase treatment of bipolar disorder. The specific role of LAR in comparison to other atypical antipsychotics, and the limitations of available studies will be discussed from the perspectives of efficacy, tolerability, and sequential positioning in treatment guidelines.

Açıklama

WOS: 000267777400002
PubMed: 19562274

Anahtar Kelimeler

adherence, bipolar disorder, long-acting risperidone, maintenance phase, risperidone

Kaynak

Advances In Therapy

WoS Q Değeri

Q4

Scopus Q Değeri

Q1

Cilt

26

Sayı

6

Künye