Can end-tidal CO2 measurement replace arterial partial CO2 in emergency department respiratory distress management?

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dc.authoridTASDEMIR, MURAT/0000-0002-7887-0626
dc.authoridBogan, Mustafa/0000-0002-3238-1827
dc.authoridDemir, Mehmet Cihat/0000-0002-0106-3383
dc.authoridSelki, Kudret/0000-0002-3495-4991
dc.authoridErdem, Emre/0009-0007-1848-8787
dc.authoridSenguldur, Erdinc/0000-0002-3978-9534
dc.contributor.authorSelki, Kudret
dc.contributor.authorDemir, Mehmet Cihat
dc.contributor.authorSenguldur, Erdinc
dc.contributor.authorErdem, Emre
dc.contributor.authorGuldal, Hatice
dc.contributor.authorTasdemir, Murat
dc.contributor.authorKiciroglu, Alp Kaan Furkan
dc.date.accessioned2025-10-11T20:48:32Z
dc.date.available2025-10-11T20:48:32Z
dc.date.issued2024
dc.departmentDüzce Üniversitesien_US
dc.description.abstractObjective: To assess the feasibility of using end-tidal carbon dioxide (EtCO2) as a non-invasive substitute for partial pressure of arterial carbon dioxide (PaCO2) in emergency department (ED) triage and follow-up, and to explore the potential of partial pressure of venous carbon dioxide (PvCO(2)) as an alternative to PaCO2. Design: Prospective cross-sectional study. Setting: Tertiary university hospital. Patients or participants: 97 patients presenting with acute respiratory distress to the ED. Interventions: EtCO2, arterial blood gases, and venous blood gases measured at admission (0 min), 60 min, and 120 min. Main variables of interest: CO2 levels. Results: Among 97 patients (mean age: 70.93 +/- 9.6 years; 60.8% male), EtCO2 > 45 mmHg at admission showed strong positive correlations with PaCO2 and PvCO(2) (r = 0.844, r = 0.803; p < 0.001, respectively). Significant positive correlation was observed between 60-min EtCO2 and PaCO2 (r = 0.729; p < 0.001). Strong correlation between PaCO2 and PvCO(2) at 120 min when EtCO2 > 45 mmHg (r = 0.870; p < 0.001). EtCO2 was higher in hospitalized patients compared to discharged ones. Conclusions: EtCO2 appears promising as a substitute for PaCO2 in ED patients with acute respiratory distress within the initial two hours of treatment. Venous blood gas sampling offers a less invasive alternative to arterial sampling, facilitating simultaneous blood tests. (c) 2024 Elsevier Espana, S.L.U. and SEMICYUC. All rights are reserved, including those for text and data mining, AI training, and similar technologies.en_US
dc.identifier.doi10.1016/j.medin.2024.03.021
dc.identifier.endpage519en_US
dc.identifier.issn0210-5691
dc.identifier.issn1578-6749
dc.identifier.issue9en_US
dc.identifier.pmid38692991en_US
dc.identifier.scopus2-s2.0-85202047124en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage511en_US
dc.identifier.urihttps://doi.org/10.1016/j.medin.2024.03.021
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21951
dc.identifier.volume48en_US
dc.identifier.wosWOS:001317083000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Espana Sluen_US
dc.relation.ispartofMedicina Intensivaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectEnd-tidal carbon dioxideen_US
dc.subjectRespiratory distressen_US
dc.subjectArterial carbon dioxideen_US
dc.subjectVenous carbon dioxideen_US
dc.subjectEmergency departmenten_US
dc.titleCan end-tidal CO2 measurement replace arterial partial CO2 in emergency department respiratory distress management?en_US
dc.typeArticleen_US

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