Preoperative therapeutic plasmapheresis in thyrotoxic patients who did not effectively treated with antithyroid drugs, iodine and corticosteroid

dc.contributor.authorAydın, Yusuf
dc.contributor.authorTütüncü, Yasemin Ateş
dc.contributor.authorBerker, Dilek
dc.contributor.authorIşık, Serhat
dc.contributor.authorÖzoğuz, Ufuk
dc.contributor.authorGüler, Serdar
dc.date.accessioned2020-04-30T13:33:08Z
dc.date.available2020-04-30T13:33:08Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: Preoperative treatment options in thyrotoxic patients are antithyroid drugs, potassium iodide, beta blockers and corticosteroids. Sometimes these treatment regimens have not been so successful for the patients to make them ready for the operation. So we thought that plasmapheresis (PP) could be an alternative to these treatments. Methods: Two thyrotoxic patients with Graves' disease and one patient with toxic multinodular goiter were included in the study. All patients were candidates to surgical operation due to the contraindication of other medical treatment choices. On admission, all patients had severe uncontrolled hyperthyroidism. In order to prepare our patients to operation, all the patients were given beta blockers and inorganic potassium iodide and corticosteroid at first but disease control could not be achieved in terms of thyrotoxicosis. So PP was performed at an average of 3 to 5 sessions. Results: After PP, all patients' thyroid hormone concentrations were significantly reduced. One patient had an anaphylactic reaction during 3th session of PP. Total thyroidectomy was performed to all patients without any complications. Conclusions: We concluded that PP could be used as an alternative therapeutic option in the preoperative management of severe thyrotoxic patients. © 2010 Düzce Medical Journal.en_US
dc.identifier.endpage54en_US
dc.identifier.issn1307671X
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage50en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/554
dc.identifier.volume12en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDuzce Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPlasmapheresis; Thyroid surgery; Thyrotoxicosisen_US
dc.titlePreoperative therapeutic plasmapheresis in thyrotoxic patients who did not effectively treated with antithyroid drugs, iodine and corticosteroiden_US
dc.typeArticleen_US

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