Impact of Body Mass Index on Left Ventricular Diastolic Dysfunction

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dc.contributor.authorÇil, Habib
dc.contributor.authorBulur, Serkan
dc.contributor.authorTürker, Yasin
dc.contributor.authorKaya, Ahmet
dc.contributor.authorAlemdar, Recai
dc.contributor.authorKarabacak, Ahmet
dc.contributor.authorÖzhan, Hakan
dc.date.accessioned2020-04-30T23:18:25Z
dc.date.available2020-04-30T23:18:25Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000306190100012en_US
dc.descriptionPubMed: 22486526en_US
dc.description.abstractBackground: The prevalence of obesity is increasing in the developed and developing world. It is an independent risk factor for heart failure. Left ventricular (LV) diastolic dysfunction has been demonstrated to be a strong predictor of heart failure. In the present study we aimed to assess the impact of body weight on LV diastolic function. Methods: The study was conducted on 2,228 participants (1,424 women, 804 men with a mean age of 49). Traditional and tissue Doppler echocardiographic examination were performed in all of the participants. The demographic and echocardiographic data were compared. Multivariate logistic regression analysis was used to assess the independent predictors of association of LV diastolic function. The study sample was divided into four groups: group 1 (body mass index [BMI] < 25.0 kg/m2), group 2 (BMI 25.029.9 kg/m2), group 3 (BMI = 3039.9 kg/m2), and group 4 (BMI = 40 kg/m2). Results: Septal E was significantly lower in groups 2 and 3 compared to group 1 (P = 0.003). Septal A and septal A were significantly higher whereas septal E and lateral E were significantly lower in the groups 2, 3, and 4 compared to the normal weight group (P < 0.001). Lateral A, deceleration time, and ejection time were significantly higher in obese when compared to the normal weight (P = 0.025, P < 0.001, and P = 0.009, respectively). The E/E ratio was significantly higher in groups 2, 3, and 4 compared to the group 1 (P < 0.001). Logistic regression analysis revealed that age, BMI (OR = 1.060 [95% CI = 1.040 and 1.080]; P < 0.001), hypertension, and diabetes mellitus were independent predictors of LV diastolic dysfunction. Conclusion: BMI is an independent predictor of LV diastolic dysfunction along with age, hypertension, and diabetes mellitus. (Echocardiography 2012;29:647-651)en_US
dc.identifier.doi10.1111/j.1540-8175.2012.01688.xen_US
dc.identifier.endpage651en_US
dc.identifier.issn0742-2822
dc.identifier.issn1540-8175
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage647en_US
dc.identifier.urihttps://doi.org/10.1111/j.1540-8175.2012.01688.x
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3288
dc.identifier.volume29en_US
dc.identifier.wosWOS:000306190100012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEchocardiography-A Journal Of Cardiovascular Ultrasound And Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbody mass indexen_US
dc.subjectdiastolic dysfunctionen_US
dc.subjecttissue Doppleren_US
dc.titleImpact of Body Mass Index on Left Ventricular Diastolic Dysfunctionen_US
dc.typeArticleen_US

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