Amatoxin and phallotoxin concentration in Amanita phalloides spores and tissues

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dc.contributor.authorKaya, Ertuğrul
dc.contributor.authorKarahan, Selim
dc.contributor.authorBayram, Recep
dc.contributor.authorYaykaşlı, Kürşat Oğuz
dc.contributor.authorÇolakoğlu, Serdar
dc.contributor.authorSarıtaş, Ayhan
dc.date.accessioned2020-04-30T22:39:06Z
dc.date.available2020-04-30T22:39:06Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionSaritas, Ayhan/0000-0002-4302-1093; Yaykasli, Kursat/0000-0001-7550-6370; Saritas, Ayhan/0000-0002-4302-1093; Kaya, Ertugrul/0000-0003-0081-682Xen_US
dc.descriptionWOS: 000365745600013en_US
dc.descriptionPubMed: 23719849en_US
dc.description.abstractMost of the fatal cases of mushroom poisoning are caused by Amanita phalloides. The amount of toxin in mushroom varies according to climate and environmental conditions. The aim of this study is to measure -, -, and -amanitin with phalloidin and phallacidin toxin concentrations. Six pieces of A. phalloides mushrooms were gathered from a wooded area of Duzce, Turkey, on November 23, 2011. The mushrooms were broken into pieces as spores, mycelium, pileus, gills, stipe, and volva. -, -, and -Amanitin with phalloidin and phallacidin were analyzed using reversed-phase high-performance liquid chromatography. As a mobile phase, 50 mM ammonium acetate + acetonitrile (90 + 10, v/v) was used with a flow rate of 1 mL/min. C18 reverse phase column (150 x 4.6 mm; 5 mu m particle) was used. The least amount of -amanitin toxins was found at the mycelium. The other toxins found to be in the least amount turned out to be the ones at the spores. The maximum amounts of amatoxins and phallotoxin were found at gills and pileus, respectively. In this study, the amount of toxin in the spores of A. phalloides was published for the first time, and this study is pioneering to deal with the amount of toxin in mushrooms grown in Turkey.en_US
dc.identifier.doi10.1177/0748233713491809en_US
dc.identifier.endpage1177en_US
dc.identifier.issn0748-2337
dc.identifier.issn1477-0393
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1172en_US
dc.identifier.urihttps://doi.org/10.1177/0748233713491809
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2600
dc.identifier.volume31en_US
dc.identifier.wosWOS:000365745600013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofToxicology And Industrial Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAmanita phalloidesen_US
dc.subjectamanitinen_US
dc.subjectphallotoxinen_US
dc.subjectHPLCen_US
dc.titleAmatoxin and phallotoxin concentration in Amanita phalloides spores and tissuesen_US
dc.typeArticleen_US

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