Prevalence of Hepatitis B Infection among Schoolchildren in Southeast Turkey

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dc.contributor.authorDikici, Bünyamin
dc.contributor.authorUzun, Hakan
dc.contributor.authorGözü, Ayfer
dc.contributor.authorFidan, Mücahit
dc.date.accessioned2020-04-30T23:21:35Z
dc.date.available2020-04-30T23:21:35Z
dc.date.issued2009
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptiondikici, bunyamin/0000-0001-7572-6525en_US
dc.descriptionWOS: 000265263900021en_US
dc.description.abstractAim: Hepatitis B virus (HBV) infection is a worldwide health problem. The objectives of this study were to determine the impact of the Expanded Programme on Immunization (EPI) on the prevalence of HBsAg carrier rate and immunity developed against HBV infection among schoolchildren in southeast Turkey. Materials and Methods: The study population consisted of 147,200 healthy schoolchildren between 6 to 17 years of age living in the Mardin area. A total of 802 children were randomly selected by systematic sampling method. Hepatitis B surface antigen (HBsAg), antibody to HBsAg (anti-HBs), and antibody to hepatitis B core antigen (anti-HBc) were analyzed in blood samples by enzyme-linked immunosorbent assay (ELISA General Biological Corp., Taiwan). Results: This study involved 420 (52.4%) male and 382 female (47.6%) schoolchildren with a mean age of 10.4 +/- 2.3 years. The overall anti-HBs. anti-HBc, and HBsAg were positive in 724 (90.2%), 56 (7%), and 22 (2.7%) children. respectively. The overall HBV seroprevalence rate was 2.7%. Conclusions: The introduction of the national EPI has successfully decreased the HBV seropositivity possibly by preventing perinatal and horizontal HBV transmission among schoolchildren in southeast Turkey.en_US
dc.identifier.endpage293en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage289en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4218
dc.identifier.volume39en_US
dc.identifier.wosWOS:000265263900021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis Ben_US
dc.subjectprevalenceen_US
dc.subjectvaccineen_US
dc.titlePrevalence of Hepatitis B Infection among Schoolchildren in Southeast Turkeyen_US
dc.typeArticleen_US

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