Effect of Adjunctive Thrombus Aspiration on In-Hospital and 3-Year Outcomes in Patients With ST-Segment Elevation Myocardial Infarction and Large Native Coronary Artery Thrombus Burden

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dc.contributor.authorKeskin, Muhammed
dc.contributor.authorKaya, Adnan
dc.contributor.authorTatlısu, Mustafa Adem
dc.contributor.authorUzman, Osman
dc.contributor.authorBörklü, Edibe Betül
dc.contributor.authorÇinier, Göksel
dc.contributor.authorKozan, Ömer
dc.date.accessioned2020-05-01T09:11:35Z
dc.date.available2020-05-01T09:11:35Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionCinier, Goksel/0000-0001-5064-1816; Keskin, Muhammed/0000-0002-4938-0097en_US
dc.descriptionWOS: 000416614300002en_US
dc.descriptionPubMed: 28864320en_US
dc.description.abstractAlthough the long-term clinical benefit of adjunctive thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) remains controversial, the impact of TA in patients with large thrombus has not been evaluated. The aim of the present study was to investigate the effect of adjunctive TA during PPCI on clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) and a large thrombus. We assessed the effect of adjunctive TA on in-hospital and 3-year clinical outcomes in 627 patients with STEMI and a large thrombus in the native coronary artery. The cumulative 3-year incidence of all-cause death was not significantly different between the 2 groups (91.5% vs 89.0%, log-rank test p = 0.347). After adjusting for confounders, the risk of all-cause death in the TA group was not significantly lower than that in the non-TA group (hazard ratio 1.11, 95% confidence interval 0.60 to 3.54, p = 0.674). The adjusted risks of target lesion revascularization, nonfatal acute myocardial infarction, and stent thrombosis were also not significantly different between the 2 groups. In conclusion, adjunctive TA during PPCI was not associated with better in-hospital and 3-year all-cause deaths in patients with STEMI and a large coronary artery thrombus. (C) 2017 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.amjcard.2017.07.079en_US
dc.identifier.endpage1714en_US
dc.identifier.issn0002-9149
dc.identifier.issn1879-1913
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1708en_US
dc.identifier.urihttps://doi.org/10.1016/j.amjcard.2017.07.079
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5677
dc.identifier.volume120en_US
dc.identifier.wosWOS:000416614300002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherExcerpta Medica Inc-Elsevier Science Incen_US
dc.relation.ispartofAmerican Journal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEffect of Adjunctive Thrombus Aspiration on In-Hospital and 3-Year Outcomes in Patients With ST-Segment Elevation Myocardial Infarction and Large Native Coronary Artery Thrombus Burdenen_US
dc.typeArticleen_US

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