Efficiency of radioactive I-131 therapy in geriatric patients with toxic nodular goiter

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dc.contributor.authorErkan, Melih Engin
dc.contributor.authorDemirin, Hilmi
dc.contributor.authorAşık, Muhammed
dc.contributor.authorCelbek, Gökhan
dc.contributor.authorYıldırım, Mustafa
dc.contributor.authorAydın, Yusuf
dc.contributor.authorDoğan, Ahmet Semih
dc.date.accessioned2020-05-01T09:12:09Z
dc.date.available2020-05-01T09:12:09Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000327389100021en_US
dc.descriptionPubMed: 23211880en_US
dc.description.abstractBackground and aims: The success of I-131 therapy in geriatric patients who were referred to an endocrinology clinic with toxic nodular goiter and who lived in iodine-deficiency regions was studied. Materials and methods: Patients older than 60 years who received I-131 therapy were included via retrospective data analyses. Fifty-nine patients between 60 and 82 years of age were enrolled in the study. The patients received an oral capsular form of I-131 (10-25 mCi) and were followed up for 1 year with clinical and laboratory results. Euthyroid or hypothyroid status at the end of the year after treatment was deemed to be a response to treatment. Results: Of the 21 (36%) male and 38 (64%) female patients, 29 (49%) had a solitary toxic nodule and 30 (5 1%) had toxic multinodular goiter. Twenty-nine (49%) of the patients received propylthiouracil therapy. At the end of the year, 38 (64%) patients were euthyroid, 11 (19%) were hypothyroid, and 10 (17%) were thyrotoxic. Forty-nine (83%) patients who were euthyroid and hypothyroid were considered responders. Conclusion: Geriatric patients with toxic nodular goiter were shown to have a high response rate to I-131 therapy. Thus, we suggest that radioactive iodine treatment should be the first-line treatment in these patients. (C) 2012, Editrice Kurtisen_US
dc.identifier.doi10.3275/8759en_US
dc.identifier.endpage717en_US
dc.identifier.issn1594-0667
dc.identifier.issn1720-8319
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage714en_US
dc.identifier.urihttps://doi.org/10.3275/8759
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5894
dc.identifier.volume24en_US
dc.identifier.wosWOS:000327389100021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAging Clinical And Experimental Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGeriatricsen_US
dc.subjecthyperthyroidismen_US
dc.subjectiodine radioisotopesen_US
dc.subjectthyroid noduleen_US
dc.titleEfficiency of radioactive I-131 therapy in geriatric patients with toxic nodular goiteren_US
dc.typeArticleen_US

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