Prescribing Trends of Atypical Antipsychotic Drugs in an Outpatient Unit of a Child and Adolescent Clinic in Turkey

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dc.contributor.authorYektaş, Çiğdem
dc.contributor.authorTufan, Ali Evren
dc.date.accessioned2020-04-30T23:21:32Z
dc.date.available2020-04-30T23:21:32Z
dc.date.issued2018
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionYektas, Cigdem/0000-0002-5951-7253; Tufan, ALI EVREN/0000-0001-5207-6240en_US
dc.descriptionWOS: 000423714400006en_US
dc.descriptionPubMed: 29303800en_US
dc.description.abstractObjective Use of antipsychotic agents in the management of various psychopathologies in Child and Adolescent Psychiatric practice is gradually increasing. This study aimed to evaluate the sociodemographic and clinical features of children and adolescents who applied to an outpatient clinic of child and adolescent psychiatry department in Turkey and were prescribed atypical antipsychotics. Method Patients with prescription codes of ATC N05A (except N05AN lithium) were accepted to denote those with atypical antipsychotic treatment. Sociodemographic and clinical variables, pharmacological mechanisms and groups and use of multiple agents for 212 patients with atypical antipsychotic treatment were collected and recorded. Results Patients (6.6%) evaluated within a year were prescribed antipsychotic agents (APs). The majority of the sample consisted of adolescents and especially females. The most common diagnoses managed with atypical antipsychotic were attention-deficit/hyperactivity disorder, MDD, and mental retardation/intellectual disability in decreasing frequency. Males with attention-deficit/hyperactivity disorder, CD, and autism spectrum disorders and females with MDD and PTSD were more frequently prescribed APs. Most common indications were irritability, impulsivity, and self-harming behaviors. Most common agents were risperidone, aripiprazole, and quetiapine in decreasing order of frequency. Most common adverse effects were reported as sedation, increased appetite, and hyperprolactinemia. Conclusions Our results support the prevalence of off-label use of AP agents in managing various childhood psychopathologies also in Turkey. Further studies from multiple centers and using reliable and valid measurements are needed to determine the extent and predictors of AP use in outpatient samples from different child and adolescent centers.en_US
dc.identifier.doi10.1097/WNF.0000000000000263en_US
dc.identifier.endpage27en_US
dc.identifier.issn0362-5664
dc.identifier.issn1537-162X
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage23en_US
dc.identifier.urihttps://doi.org/10.1097/WNF.0000000000000263
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4210
dc.identifier.volume41en_US
dc.identifier.wosWOS:000423714400006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofClinical Neuropharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectatypical antipsychoticsen_US
dc.subjectoff-label useen_US
dc.subjectchilden_US
dc.subjectadolescenten_US
dc.titlePrescribing Trends of Atypical Antipsychotic Drugs in an Outpatient Unit of a Child and Adolescent Clinic in Turkeyen_US
dc.typeReview Articleen_US

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