An in-vitro assessment of bisphenol a release from thermoplastic orthodontic appliances exposed to various beverages

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dc.authoridArslan, Basak/0000-0001-6457-719X
dc.authoridYILDIRIM, Ertan/0000-0002-4083-3408
dc.authoridtuncer, cumhur/0000-0003-3275-5718
dc.contributor.authorAvan, Basak Arslan
dc.contributor.authorBodur, Onur Can
dc.contributor.authorYildirim, Ertan
dc.contributor.authorOsanmaz, Akin
dc.contributor.authorTuncer, Cumhur
dc.contributor.authorTuncer, Burcu Balos
dc.date.accessioned2025-10-11T20:48:09Z
dc.date.available2025-10-11T20:48:09Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackgroundThermoplastic orthodontic appliances have been used as retention devices for years and gaining popularity as aligners, alternative to fixed orthodontic mechanics. This study aims to assess Bisphenol-A (BPA) release from thermoplastic orthodontic appliances exposed to different beverages.MethodsThe appliances in this study were enrolled from aligners of Invisalign, ClearCorrect, and thermoplastic retention device, Essix ACE. Five different beverages (pure water, whole milk, coke, orange juice, filtered coffee) were determined and 5 glass tubes containing 10 ml of each beverage formed experiment groups. Appliance samples from each brand (with 0.50 +/- 0.0082 g weight) were inserted in glass tubes and left in room temperature for 1 h. Later, samples were removed and Flow Injection Liquid Chromatography/Mass-Mass Spectrometry (FIA-LC/MS-MS) analysis was performed to evaluate BPA release. Five glass tubes for each beverage group, which did not contain any appliance, were also analyzed with the same technique to detect the possible pre-existing BPA levels in the liquids.ResultsFIA-LC/MS-MS analysis showed no measurable amount of BPA in pure water and any beverage group. BPA was also not detected in samples without appliances.ConclusionBPA release was not detected from thermoplastic orthodontic appliances after 1 h of incubation in beverages. Within the limitations, different types of beverages were not found to affect BPA release from thermoplastic orthodontic materials. From a clinical perspective, further in-vivo studies will be useful with larger samples and longer term investigations.en_US
dc.identifier.doi10.1186/s12903-025-06066-3
dc.identifier.issn1472-6831
dc.identifier.issue1en_US
dc.identifier.pmid40399894en_US
dc.identifier.scopus2-s2.0-105005599166en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s12903-025-06066-3
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21751
dc.identifier.volume25en_US
dc.identifier.wosWOS:001493127600010en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Oral Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectThermoplastic orthodontic appliancesen_US
dc.subjectClear alignersen_US
dc.subjectBisphenol-Aen_US
dc.subjectBeverageen_US
dc.subjectOrthodonticsen_US
dc.titleAn in-vitro assessment of bisphenol a release from thermoplastic orthodontic appliances exposed to various beveragesen_US
dc.typeArticleen_US

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