Cancer, platelet distribution width, and total protein levels as predictors of rebleeding in upper gastrointestinal bleeding

dc.authoridTatlıparmak, Ali Cankut/0000-0002-6729-5021
dc.authorwosidTatlıparmak, Ali Cankut/ACG-9879-2022
dc.contributor.authorTatliparmak, Ali Cankut
dc.contributor.authorDikme, Ozlem
dc.contributor.authorDikme, Özgür
dc.contributor.authorTopaçoğlu, Hakan
dc.date.accessioned2023-07-26T11:54:45Z
dc.date.available2023-07-26T11:54:45Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Acil Tıp Ana Bilim Dalıen_US
dc.description.abstractBackground: Rebleeding is associated with poor outcomes in upper gastrointestinal bleeding (UGIB). Identifying predictors of rebleeding can assist in risk assessment. The aim of the study is to investigate the factors affecting rebleeding in patients with UGIB admitted to the emergency department.Methods: This retrospective, observational, cross-sectional study was conducted on patients with UGIB presented to the emergency department. Patients who did not arrest in the first 24 h, who were not diagnosed with GI malignancy, and who were clinically diagnosed with UGIB were included in the study. Patient demographic characteristics, hemodynamic parameters, patient parameters, and bleeding that may affect rebleeding were evaluated. The primary endpoint was rebleeding within 7 days.Results: The study included 371 patients. A total of 55 patients (14.8%) had rebleeding within 7 days, and 62 patients (16.7%) presented without bleeding manifestations. Rebleeding rates were higher in those who presented with bloody or coffee-ground vomitus, had a diagnosis of cancer, had blood in their nasogastric tube, and had peptic ulcers due to endoscopy. Mean cell hemoglobin concentration, lymphocyte, albumin, and total protein values of patients with rebleeding were low; red blood cell distribution width, neutrophil count, platelet distribution width (PDW), and neutrophil lymphocyte ratio were high. In-hospital mortality and 30-day mortality values of patients with rebleeding were significantly increased. In the multivariate analysis, cancer, PDW, and total protein levels were statistically significant.Conclusion: The presence of cancer, low total protein level, and high PDW are effective parameters in predicting 7-day rebleeding in patients with UGIB admitted to the emergency department.en_US
dc.identifier.doi10.7717/peerj.14061
dc.identifier.issn2167-8359
dc.identifier.pmid36128193en_US
dc.identifier.scopus2-s2.0-85138156871en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.7717/peerj.14061
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12913
dc.identifier.volume10en_US
dc.identifier.wosWOS:000862318100002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTopaçoğlu, Hakan
dc.language.isoenen_US
dc.publisherPeerj Incen_US
dc.relation.ispartofPeerjen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectUpper Gastrointestinal Bleeding; Rebleeding; Predictors Of Rebleedingen_US
dc.subjectMulticenter; Management; Endoscopy; Mortality; Timeen_US
dc.titleCancer, platelet distribution width, and total protein levels as predictors of rebleeding in upper gastrointestinal bleedingen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Yükleniyor...
Küçük Resim
İsim:
12913.pdf
Boyut:
730.47 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text