An evaluation of suspected cases of Hantavirus infection admitted to a tertiary care university hospital in Duzce, Turkey, between 2012 and 2018

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Tarih

2021

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Yayıncı

Tubitak Scientific & Technical Research Council Turkey

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background/aim: Hantavirus is a rodent borne zoonosis caused by the members of the virus family Bunyaviridae, genus Hantavirus. In this study, we aimed to determine the role of peripheral blood leukocyte ratio in differential diagnosis of Hantavirus disease. Materials and methods: The medical records of patients at the Duzce University Medical Faculty were examined retrospectively. A total of 20 patients diagnosed with hantavirus infection confirmed by serologic tests were included in the study (Group 1). The other group consisted of 30 patients suspected of hantavirus infection but found negative (Group 2). Demographic, clinical and laboratory characteristics, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and lymphocyte/monocyte (LMR) ratios of both groups were compared. Results: As a result of the istatistics analysis, no difference was found between the groups' age, sex, and clinical complaints except lethargy-weakness (P = 0.004) and diarrhea (P < 0.001). Hemogram analysis showed a significant difference between the groups in terms of leukocyte, hemoglobin, hematocrit, platelet, mean platelet volume (P < 0.05) and PLR (P = 0.001) and LMR (P = 0.003) values from peripheral blood leukocyte ratios. Conclusion: In conclusion, NLR, PLR, and LMR ratios may be useful for clinicians in differential diagnosis of Hantavirus in patients presenting with similar symptoms of Hantavirus disease.

Açıklama

Anahtar Kelimeler

Hantaviruses, neutrophil, lymphocyte ratio (NLR), platelet, lymphocyte ratio (PLR), monocyte, lymphocyte ratio (PLR), predictive factors, Turkey, Hemorrhagic-Fever, Lymphocyte Ratio, Renal Syndrome, Neutrophil, Region, Puumala

Kaynak

Turkish Journal Of Medical Sciences

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

51

Sayı

1

Künye