Predictivity of fatty liver index for non-alcoholic fatty liver disease in lean females with polycystic ovary syndrome

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dc.contributor.authorArıkan, Didem
dc.contributor.authorÖnmez, Attila
dc.contributor.authorAksu, Erson
dc.contributor.authorTasdemir, Nicel
dc.date.accessioned2023-07-26T11:54:44Z
dc.date.available2023-07-26T11:54:44Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractBackground: Fatty liver index (FLI) is a simple tool used to predict non-alcoholic fatty liver disease (NAFLD). The role of FLI in polycystic ovary syndrome (PCOS) for the prediction of NAFLD has not been elucidated. Methods: This case-control study was from January 2014 to January 2016. Anthropometric measurements, biochemical testing, and abdominal ultrasonography were performed in 83 premenopausal otherwise healthy women with PCOS and 58 controls. NAFLD was diagnosed by ultrasound. The predictivity of FLI for NAFLD in lean and overweight/obese females with PCOS was analyzed. Results: The ??-glutamyl transferase levels were significantly higher in the females with PCOS than in the controls (p = 0.001). In women with PCOS, FLI was significantly higher in females with NAFLD comparing to those without NAFLD (47.1 ?? 33.6 vs. 16.9 ?? 21.6; p = 0.001). For the PCOS group, Body Mass Index had the strongest relationship with FLI (p < 0.05, r = 0.908). FLI < 30 was calculated for all the lean females. The lean females with PCOS had a significantly higher rate of NAFLD (27.5% vs. 8.8%; p = 0.041) than lean controls. Conclusion: An FLI < 30 was not sufficient to rule out NAFLD in the lean PCOS patients.en_US
dc.identifier.doi10.4314/ahs.v22i1.75
dc.identifier.endpage656en_US
dc.identifier.issn1680-6905
dc.identifier.issn1729-0503
dc.identifier.issue1en_US
dc.identifier.pmid36032442en_US
dc.identifier.scopus2-s2.0-85130047206en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage648en_US
dc.identifier.urihttps://doi.org/10.4314/ahs.v22i1.75
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12909
dc.identifier.volume22en_US
dc.identifier.wosWOS:000796221000075en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÖnmez, Attila
dc.language.isoenen_US
dc.publisherMakerere Univ, Coll Health Sciences,Sch Meden_US
dc.relation.ispartofAfrican Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectPolycystic Ovary Syndrome; Non-Alcoholic Fatty Liver Disease; Fatty Liver Indexen_US
dc.subjectHepatic Steatosis; Metabolic Syndrome; Prevalence; Women; Obesity; Hyperandrogenism; Association; Risken_US
dc.titlePredictivity of fatty liver index for non-alcoholic fatty liver disease in lean females with polycystic ovary syndromeen_US
dc.typeArticleen_US

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