Evaulation of atrial conduction abnormalities and left atrial mechanical functions in patients with subclinical thyroid disorders

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dc.contributor.authorÖztürk, Serkan
dc.contributor.authorDikbaş, Oğuz
dc.contributor.authorBaltacı, Davut
dc.contributor.authorÖzyaşar, Mehmet
dc.contributor.authorErdem, Alim
dc.contributor.authorAyhan, Selim Suzi
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2020-05-01T12:14:13Z
dc.date.available2020-05-01T12:14:13Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAlcelik, Aytekin/0000-0002-3156-1076en_US
dc.descriptionWOS: 000310110900006en_US
dc.descriptionPubMed: 22933164en_US
dc.description.abstractIntroduction: Changes of thyroid hormones levels may lead to effects, not only in ventricular function, but also atrial function. The aim of this study was to investigate left atrial (LA) mechanical functions, atrial electromechanical coupling and P wave dispersion in patients with subclinical thyroid disorders. Material and methods: Eighty patients with subclinical thyroid disorders and forty controls were included. A diagnosis of subclinical thyroid disorders were reached with increased or decreased serum TSH and normal free T4 (fT4) levels. LA volumes were measured using the biplane area length method and LA active and passive emptying volumes and fraction were calculated. Intra- and interatrial electromechanical delay were measured by tissue Doppler imaging (TDI). Results: All groups had similar demographic findings. LA mechanical functions significantly impaired in subclinical thyroid disorders than control group. Intra- and Interatrial delay, were measured significantly higher in patients with subclinical thyroid disorders than control group. PA lateral and interatrial delay were positively correlated with TSH (r = 0.507, p = 0.006 and r = 0.455, p = 0.015, respectively) in subclinical hypothyroid patients. There was negative correlation between TSH and interatrial delay (r = -0.492,p = 0.006) in subclinical hyperthyroid patients. Linear multivariate regression analysis demonstrated that, TSH was the only an independent factor of interatrial delay in patients with subclinical thyroid disorders. Conclusions: This study showed that impaired LA mechanical and electromechanical function in subclinical thyroid disorders. TSH was an independent determinant of interatrial delay. Prolonged atrial electromechanical coupling time and impaired mechanical atrial functions may be related to the increased incidence of arrhythmias. (Endokrynol Pol 2012; 63 (4): 286-293)en_US
dc.identifier.doi10.1016/S0167-5273(12)70134-1en_US
dc.identifier.endpage293en_US
dc.identifier.issn0423-104X
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage286en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6337
dc.identifier.urihttps://doi.org/10.1016/S0167-5273(12)70134-1
dc.identifier.volume63en_US
dc.identifier.wosWOS:000310110900006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofEndokrynologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectthyroid hormonesen_US
dc.subjectatrial functionen_US
dc.subjectinteratrial delayen_US
dc.titleEvaulation of atrial conduction abnormalities and left atrial mechanical functions in patients with subclinical thyroid disordersen_US
dc.typeArticleen_US

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