Increased levels of red cell distribution width is correlated with presence of left atrial stasis in patients with non-valvular atrial fibrillation

Basit Öğe Kaydı
dc.contributor.authorKaya, Adnan
dc.contributor.authorTürkkan, Ceyhan
dc.contributor.authorAlper, Ahmet Taha
dc.contributor.authorGüngör, Barış
dc.contributor.authorÖzcan, Kazım Serhan
dc.contributor.authorTatlısu, Mustafa Adem
dc.contributor.authorKayapınar, Osman
dc.date.accessioned2020-04-30T23:18:29Z
dc.date.available2020-04-30T23:18:29Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionGungor, Baris/0000-0002-8883-117Xen_US
dc.descriptionWOS: 000408984000010en_US
dc.descriptionPubMed: 28752145en_US
dc.description.abstractOBJECTIVE: Red cell distribution width (RDW) and neutrophil to lymphocyte ratio (NLR) have been found to be associated with non-valvular atrial fibrillation (AF) and cardiovascular diseases. However, correlation of these parameters with presence of left atrial (LA) thrombus and/or spontaneous echo contrast (SEC) in patients with non-valvular AF has not been clarified. This study was an investigation of correlation of RDW, NLR, and clinical risk factors with LA thrombus and dense SEC in patients with non-valvular AF in the Turkish population. METHODS: The demographic, laboratory, and echocardiographic properties of 619 non-valvular AF patients who underwent transesophageal echocardiography (TEE) examination before direct current cardioversion (DCCV) or AF ablation treatment were retrospectively investigated. Complete blood count (CBC) and biochemical parameters were studied 6 to 12 hours before TEE examination. Left atrial stasis (LAS) markers were noted as presence of left atrial/left atrial appendage (LA/LAA) thrombus or dense spontaneous echo contrast (DSEC). RESULTS: Total of 325 (52%) patients with LAS were compared with 294 patients (48%) without LAS. In the LAS group, there were 274 (84%) patients with LA/LAA thrombus and 51 (16%) patients with DSEC. LAS (+) group, values for RDW (14.85 +/- 1.48 vs. 13.77 +/- 1.30; p<0.01), NLR (2.38 [1.58], vs. 2.10 [1.35]; p<0.01) and C-reactive protein (0.95 [0.61] vs. 0.88 [0.60] mg/L; p<0.01) were significantly higher than seen in LAS (-) group. In multivariate regression analysis, increased level of RDW, age, male gender, heart failure, duration of AF >6 months, and international normalized ratio <2 were independently correlated with presence of LAS. CONCLUSION: Our study indicated that increased level of RDW is independently correlated with higher risk for development of LAS in patients with non-valvular AF.en_US
dc.identifier.doi10.14744/nci.2017.72324en_US
dc.identifier.endpage72en_US
dc.identifier.issn2148-4902
dc.identifier.issue1en_US
dc.identifier.startpage66en_US
dc.identifier.urihttps://doi.org/10.14744/nci.2017.72324
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3343
dc.identifier.volume4en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofNorthern Clinics Of Istanbulen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLeft atrial thrombusen_US
dc.subjectnon-valvular atrial fibrillationen_US
dc.subjectred cell distribution widthen_US
dc.titleIncreased levels of red cell distribution width is correlated with presence of left atrial stasis in patients with non-valvular atrial fibrillationen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
3343.pdf
Boyut:
168.82 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu