In Vivo Genotoxicity Testing of Bentazone Herbicide in Danio rerio Erythrocytes Using the Micronucleus and Nuclear Abnormality Assays

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dc.authoridgoc rasgele, pınar/0000-0002-7558-3138en_US
dc.authorscopusid15136582600en_US
dc.authorscopusid58777699300en_US
dc.authorscopusid8280323200en_US
dc.authorwosidgoc rasgele, pınar/S-8923-2016en_US
dc.contributor.authorRasgele, Pinar Goc
dc.contributor.authorOzer, Havva
dc.contributor.authorKirankaya, Serife Gulsun
dc.date.accessioned2024-08-23T16:07:05Z
dc.date.available2024-08-23T16:07:05Z
dc.date.issued2024en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBentazone herbicide is in the benzothiadiazole group and is often used for the elimination of weeds. In this experiment, the in vivo genotoxicity of bentazone herbicide in Danio rerio erythrocytes was investigated using micronucleus and nuclear abnormality assays. Fish were exposed to three different concentrations (2.5, 5, and 10 mg/L) for 24, 48, 72, and 96 h, including the control group. When compared with the negative group, it was found that there was a statistical increase in the number of micronuclei in a concentration-dependent manner. According to the data obtained from the erythrocyte nucleolar abnormality assay, the most common abnormality for the 24-h treatment was kidney-shaped nucleus (at 10 mg/L concentration); the most common abnormality for the 48-, 72-, and 96-h treatment periods was echinocyte (at 5 and 10 mg/L concentrations). All concentrations of bentazone herbicide caused an increase in the total abnormality level in Danio rerio erythrocytes at all treatment times. These increases were concentration dependent for 24-, 72-, and 96-h treatment times, except for the 48-h treatment. Furthermore, for all treatment groups, the high concentration of bentazone herbicide (10 mg/L) caused changes on the long-short axis of the erythrocytes and the long-short axis of the nucleus, but these changes were not statistically significant. The data we obtained as a result of the study showed that bentazone herbicide is genotoxic for aquatic organisms depending on their use. Further research into different aquatic organisms is needed to investigate the genotoxicity mechanisms of bentazone herbicide in aquatic organisms.en_US
dc.identifier.doi10.1007/s11270-023-06835-2
dc.identifier.issn0049-6979
dc.identifier.issn1573-2932
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85180422892en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s11270-023-06835-2
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14487
dc.identifier.volume235en_US
dc.identifier.wosWOS:001131817600006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Int Publ Agen_US
dc.relation.ispartofWater Air and Soil Pollutionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHerbicideen_US
dc.subjectErythrocyteen_US
dc.subjectGenotoxicityen_US
dc.subjectDanio rerioen_US
dc.subjectMicronucleus assayen_US
dc.subjectPesticidesen_US
dc.titleIn Vivo Genotoxicity Testing of Bentazone Herbicide in Danio rerio Erythrocytes Using the Micronucleus and Nuclear Abnormality Assaysen_US
dc.typeArticleen_US

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