Experimental Animal Models in Obstetrics and Gynecology

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dc.authorscopusid56020070400en_US
dc.contributor.authorİlhan, M.
dc.date.accessioned2024-08-23T16:07:30Z
dc.date.available2024-08-23T16:07:30Z
dc.date.issued2024en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractThis study focuses on two major diseases affecting women's reproductive health: endometriosis and polycystic ovary syndrome (PCOS). Endometriosis is characterized as an estrogen-dependent condition, highlighting estrogen's role in understanding the disease's development and treatment strategies. Rat and mouse models are crucial for comprehending the pathophysiology of endometriosis and testing new therapeutic approaches. These models are particularly valuable in evaluating the effects of hormones and immune system modulators on endometriosis. Conversely, experimental models of PCOS emphasize the central role of hyperandrogenism in the development of this condition. Models induced by substances like dehydroepiandrosterone, testosterone propionate, and letrozole provide insights into the metabolic and endocrinological disruptions associated with PCOS. The letrozole-induced model, in particular, helps in understanding the relationship between hormonal imbalances and the onset of PCOS. Experimental models of both diseases offer critical knowledge for both basic science research and clinical applications. They provide essential data for understanding the pathophysiology of these conditions and developing new treatment strategies. This study demonstrates how findings from experimental models can improve women's reproductive health and lead to more effective treatments for these diseases. An enhanced understanding of hormonal and immune system mechanisms will guide future research and offer innovative solutions for treating these conditions. © 2024, Duzce University Medical School. All rights reserved.en_US
dc.identifier.doi10.18678/dtfd.1503734
dc.identifier.endpage78en_US
dc.identifier.issn1307-671X
dc.identifier.issueS1en_US
dc.identifier.scopus2-s2.0-85197560663en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage72en_US
dc.identifier.urihttps://doi.org/10.18678/dtfd.1503734
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14689
dc.identifier.volume26en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorİlhan, M.en_US
dc.language.isoenen_US
dc.publisherDuzce University Medical Schoolen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectendometriosisen_US
dc.subjectGynecological disordersen_US
dc.subjectpolycystic ovary syndromeen_US
dc.subjectandrostanoloneen_US
dc.subjectestrogenen_US
dc.subjectletrozoleen_US
dc.subjectprasteroneen_US
dc.subjecttestosteroneen_US
dc.subjecttestosterone propionateen_US
dc.subjecttumor necrosis factoren_US
dc.subjectanimal experimenten_US
dc.subjectanimal modelen_US
dc.subjectanimal tissueen_US
dc.subjectdrug therapyen_US
dc.subjectendometriosisen_US
dc.subjectfemaleen_US
dc.subjectgynecologic diseaseen_US
dc.subjectgynecologyen_US
dc.subjecthumanen_US
dc.subjecthyperalgesiaen_US
dc.subjectimmune systemen_US
dc.subjectmouseen_US
dc.subjectnonhumanen_US
dc.subjectobstetricsen_US
dc.subjectovary polycystic diseaseen_US
dc.subjectpathophysiologyen_US
dc.subjectpelvic painen_US
dc.subjectpharmacologyen_US
dc.subjectpregnancyen_US
dc.subjectraten_US
dc.subjectreproductive healthen_US
dc.subjectReviewen_US
dc.subjectsystematic reviewen_US
dc.titleExperimental Animal Models in Obstetrics and Gynecologyen_US
dc.title.alternativeJinekolojik Rahatsızlıklarda Kullanılan Deneysel Hayvan Modellerien_US
dc.typeReviewen_US

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