Effects of Isotretinoin Treatment on Sleep and Quality of Life in Patients with Acne Vulgaris

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dc.contributor.authorÖzlü, Emin
dc.contributor.authorErtaş, Ragıp
dc.contributor.authorÖzyurt, Kemal
dc.contributor.authorKaraatlı, İsmail
dc.contributor.authorKaradağ, Ayşe Serap
dc.date.accessioned2020-05-01T09:11:59Z
dc.date.available2020-05-01T09:11:59Z
dc.date.issued2018
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionErtas, Ragip/0000-0002-9269-2619en_US
dc.descriptionWOS: 000430876600011en_US
dc.description.abstractObjective: We aimed to investigate the effect of isotretinoin treatment on sleep and quality of life in patients with AV. Methods: 109 total patients who identified as 66 AV patients attended the dermatology outpatient clinic and started isotretinoin treatment, and 43 healthy controls, were enrolled in the study. Pittsburgh Sleep Quality Index (PSQI), short form-36 (SF-36), and Global Acne Grading System (GAGS) were administered to all patients twice; before and two months after the treatment. The results were compared with the healthy control group. Results: The pretreatment physical health scores of the patients were significantly higher than the healthy controls. No significant differences were observed between before-after isotretinoin treatment regarding physical and mental health scores in AV patients. While there were no significant differences between the pretreatment and healthy control group in terms of total PSQI scores; the scores of sleep duration were significantly lower in the pretreatment group. No significant differences were observed between before-after isotretinoin treatment regarding total PSQI and subcomponent scores in AV patients. There was a statistically significant negative correlation between pre- and post-treatment total PSQI scores and physical, mental health scores in patients with AV. Conclusion: Results of the present study suggest that isotretinoin therapy does not affect the sleep quality in patients with AV. The impairment of sleep quality negatively affects the quality of life in patients with AV. More comprehensive studies assessing the effect of isotretinoin treatment on sleep quality are needed.en_US
dc.identifier.doi10.18521/ktd.378682en_US
dc.identifier.endpage73en_US
dc.identifier.issn1309-3878
dc.identifier.issue1en_US
dc.identifier.startpage65en_US
dc.identifier.urihttps://doi.org/10.18521/ktd.378682
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5836
dc.identifier.volume10en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherDuzce Univen_US
dc.relation.ispartofKonuralp Tıp Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcne Vulgarisen_US
dc.subjectIsotretinoinen_US
dc.subjectSleep Disordersen_US
dc.subjectQuality of Lifeen_US
dc.titleEffects of Isotretinoin Treatment on Sleep and Quality of Life in Patients with Acne Vulgarisen_US
dc.typeArticleen_US

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