Deep Vein Thrombosis as a Harbinger of Malignancy in the Emergency Department

dc.authoridDemir, Mehmet Cihat/0000-0002-0106-3383;
dc.contributor.authorDemir, Mehmet Cihat
dc.contributor.authorSelki, Kudret
dc.contributor.authorDemir, Mehmet Cihat
dc.date.accessioned2025-10-11T20:47:51Z
dc.date.available2025-10-11T20:47:51Z
dc.date.issued2024
dc.departmentDüzce Üniversitesien_US
dc.description.abstractObjective: To determine whether malignancy was discovered within one year of follow-up in patients with deep vein thrombosis (DVT) in the emergency department (ED). Study Design: Descriptive study. Place and Duration of the Study: Department of Emergency Medicine, School of Medicine, Duzce University, Duzce, Turkiye, from November 2019 to November 2022. Methodology: All patients diagnosed with lower limb DVT on venous Doppler ultrasound were included in this study. Patients with a confirmed diagnosis or suspicion of malignancy were excluded. The study outcome was the discovery of malignancy within a year. DVT patients subsequently diagnosed with malignancy were grouped as secondary or idiopathic. Results: A total of 224 DVT patients without malignancy were studied. The median age of patients diagnosed with DVT was 65.5 years (47-77), of which, 51.8% were females. Malignancy was detected in 5.4% (12/224) of the patients within one year. Malignancy discovery was significantly higher in the secondary DVT group (OR = 4.52, 95% CI = 1.31-11.55; p = 0.021). Ten of 12 patients (83.3%) diagnosed with malignancy were from the genitourinary or gastrointestinal systems. Conclusion: In patients without known malignancy who were diagnosed with DVT in the ED, the rate of malignancy discovery in a one-year follow-up was 5.4%. EDs, where DVT is frequently diagnosed, are a hub of opportunities for early detection of malignancy. Arranging primary care follow-up of patients with DVT will contribute to better early diagnosis and survival rates, especially for genitourinary and gastrointestinal malignancies.en_US
dc.identifier.doi10.29271/jcpsp.2024.12.1534
dc.identifier.endpage1538en_US
dc.identifier.issn1022-386X
dc.identifier.issn1681-7168
dc.identifier.issue12en_US
dc.identifier.pmid39648392en_US
dc.identifier.scopus2-s2.0-85211700845en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1534en_US
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2024.12.1534
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21612
dc.identifier.volume34en_US
dc.identifier.wosWOS:001412770000023en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherColl Physicians & Surgeons Pakistanen_US
dc.relation.ispartofJcpsp-Journal of the College of Physiciansand Surgeons Pakistanen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectDeep vein thrombosisen_US
dc.subjectMalignancyen_US
dc.subjectEmergency departmenten_US
dc.subjectVenous Doppler ultrasounden_US
dc.titleDeep Vein Thrombosis as a Harbinger of Malignancy in the Emergency Departmenten_US
dc.typeArticleen_US

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