Evaluation of the effects of red blood cell distribution width on survival in lung cancer patients

Basit Öğe Kaydı
dc.contributor.authorKöş, Mehmet
dc.contributor.authorHocazade, Cemil
dc.contributor.authorKöş, Fahriye Tuğba
dc.contributor.authorUncu, Doğan
dc.contributor.authorKarakaş, Esra
dc.contributor.authorDoğan, Mutlu
dc.contributor.authorZengin, Nurullah
dc.date.accessioned2020-05-01T12:14:12Z
dc.date.available2020-05-01T12:14:12Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000382525900010en_US
dc.descriptionPubMed: 27358595en_US
dc.description.abstractAim of the study: Data are available indicating that red blood cell distribution width (RDW) is higher in cancer patients compared to healthy individuals or benign events. In our study, we aimed to investigate the influence of different RDW levels on survival in lung cancer patients. Material and methods: Clinical and laboratory data from 146 patients with lung cancer and 40 healthy subjects were retrospectively studied. RDW was recorded before the application of any treatment. Patients were categorised according to four different RDW cut-off values (median RDW, RDW determined by ROC curve analysis, the upper limit at the automatic blood count device, and RDW cut of value which used in previous studies). Kaplan-Meier survival analysis was used to examine the effect of RDW on survival for each cut-off level. Results: The median age of patients was 56.5 years (range: 26-83 years). The difference in median RDW between patients and the control group was statistically significant (14.0 and 13.8, respectively, p = 0.04). There was no difference with regard to overall survival when patients with RDW = 14.0 were compared to those with RDW < 14.0 (p = 0.70); however, overall survival was 3.0 months shorter in low values of its own group in each of the following cut-off values: >= 14.2 (p = 0.34), >= 14.5 (p = 0.25), >= 15 (p = 0.59), although no results were statistically significant. Discussion: We consider that the difference between low and high RDW values according to certain cut-off values may reflect the statistics of larger studies although there is a statistically negative correlation between RDW level and survival.en_US
dc.identifier.doi10.5114/wo.2016.60072en_US
dc.identifier.endpage157en_US
dc.identifier.issn1428-2526
dc.identifier.issn1897-4309
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage153en_US
dc.identifier.urihttps://doi.org/10.5114/wo.2016.60072
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6321
dc.identifier.volume20en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofWspolczesna Onkologia-Contemporary Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectprognosisen_US
dc.subjectlung canceren_US
dc.subjectblooden_US
dc.subjectRDWen_US
dc.titleEvaluation of the effects of red blood cell distribution width on survival in lung cancer patientsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
6321.pdf
Boyut:
72.79 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu