Evaluation of the effect of new generation denture base materials aged in artificial saliva at different pH levels on surface roughness and Candida albicans adhesion

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dc.authoridARSLAN, Ezgi/0000-0002-2372-3047
dc.authoridErdonmez, Demet/0000-0002-5331-2206;
dc.contributor.authorArslan, Ezgi
dc.contributor.authorAkay, Canan
dc.contributor.authorErdonmez, Demet
dc.contributor.authorAvukat, Esra Nur
dc.date.accessioned2025-10-11T20:48:09Z
dc.date.available2025-10-11T20:48:09Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractPurpose The aim of this in vitro study was to evaluate the surface roughness and Candida albicans (C. albicans) biofilm formation of conventional heat-cured and different CAD/CAM milling denture base materials, after immersion in different pH levels of artificial saliva. Materials and methods Disc-shaped samples (10 x 2 mm) (n = 10) were prepared from two brands of CAD/CAM milled and conventional heat-cured PMMA denture base materials. The samples were immersed at 37 degrees C for 21 days in different pH levels of artificial saliva. The surface roughness (Ra) of each sample was measured using a contact profilometer before and after aging. C. albicans adhesion of the samples was determined using the Crystal Violet (CV) method. Results A significant increase in roughness was observed across all material groups maintained at pH 3 (P < 0.001). At pH 7, the roughness for heat-cured PMMA and G-PMMA groups increased significantly. Although pH 14 increased roughness in all groups, this was not significant. Upon comparison of roughness values post-aging, no significant differences were noted between the groups at pH 3 and pH 7; however, the G-PMMA group exhibited significantly lower surface roughness at pH 14 (P < 0.05). Among all material groups, the highest adhesion of C. albicans was observed in the heat-cured PMMA group. (P < 0.05). Conclusions Aging at different pH values caused surface changes in denture base materials and differences in C. albicans adhesion. Although there is an increase in surface roughness in all groups, these values are lower than the plaque accumulation threshold. The highest C. albicans adhesion was observed in heat-cured PMMA samples. Considering both roughness values and Candida adhesions, it is concluded that the new generation denture base materials are suitable for clinical use and should be widely used.en_US
dc.description.sponsorshipEskisehir Osmangazi University Scientific Research Projectsen_US
dc.description.sponsorshipNo applicable.en_US
dc.identifier.doi10.1186/s12903-025-05700-4
dc.identifier.issn1472-6831
dc.identifier.issue1en_US
dc.identifier.pmid40055754en_US
dc.identifier.scopus2-s2.0-86000285189en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s12903-025-05700-4
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21752
dc.identifier.volume25en_US
dc.identifier.wosWOS:001439782500008en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Oral Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectBiofilm formationen_US
dc.subjectCAD/CAMen_US
dc.subjectCandida albicansen_US
dc.subjectCrystal violeten_US
dc.subjectPMMAen_US
dc.titleEvaluation of the effect of new generation denture base materials aged in artificial saliva at different pH levels on surface roughness and Candida albicans adhesionen_US
dc.typeArticleen_US

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