The prevalence and clinical characteristics of mitral valve prolapse in a large population-based epidemiologic study: the MELEN study

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dc.contributor.authorTürker, Yasin
dc.contributor.authorTürker, Yasin
dc.contributor.authorBaltacı, Davut
dc.contributor.authorBaşar, Cengiz
dc.contributor.authorAkkaya, M.
dc.contributor.authorÖzhan, Hakan
dc.date.accessioned2020-04-30T23:34:05Z
dc.date.available2020-04-30T23:34:05Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000357991900013en_US
dc.descriptionPubMed: 26166644en_US
dc.description.abstractOBJECTIVE: Mitral valve prolapse (MVP) is the most common cardiac valvular abnormality in industrialized countries. Its prevalence has been estimated to be between 2% to 4%. However, some studies found the prevalence of MVP less than 1% which is significantly lower than the prevalence reported in the Framingham Heart Study. The purpose of this study was to determine the prevalence, demographic, clinical and echocardiographic characteristics of MVP in a large population-based epidemiologic study. PATIENTS AND METHODS: The final cohort included 2,228 participants. Data were obtained by a validated questionnaire, physical examination of the cardiovascular system, recording of a resting electrocardiogram, transthoracic echocardiographic examination. RESULTS: The echocardiographic prevalence of MVP was 0.36%. Baseline demographic and clinical characteristics of patients were as follows; 12.5% had hypertension, 37.5% had depression, 12.5% had migraine, 12.5% had diabetes mellitus, 12.5% had diastolic dysfunction, 25% had multinodular goiter, 12.5% had diffuse goiter and 25% had hyperthyroidism. During the follow-up of 36 months no major adverse events occurred in patients with MVP during the follow-up. CONCLUSIONS: This finding suggests that MVP is a benign disorder and the prevalence of MVP is lower than previously studies. There might be a relationship between MVP and goiter, and depression.en_US
dc.identifier.endpage2212en_US
dc.identifier.issn1128-3602
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2208en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5101
dc.identifier.volume19en_US
dc.identifier.wosWOS:000357991900013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEpidemiologyen_US
dc.subjectMitral valve prolapseen_US
dc.subjectPrevalenceen_US
dc.titleThe prevalence and clinical characteristics of mitral valve prolapse in a large population-based epidemiologic study: the MELEN studyen_US
dc.typeArticleen_US

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