Clinical Presentation, Electrocardiographic Findings, and Factors Related to the Hospitalization In Mad-Honey Intoxication

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dc.contributor.authorSümerkan, Mutlu Çağan
dc.contributor.authorKalender, Erol
dc.contributor.authorKorkut, Semih
dc.contributor.authorŞimşek, Engin Ersin
dc.contributor.authorKeskin, Kudret
dc.contributor.authorGürdal, Ahmet
dc.contributor.authorSığırcı, Serhat
dc.date.accessioned2023-07-26T11:50:57Z
dc.date.available2023-07-26T11:50:57Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Aile Hekimliği Ana Bilim Dalıen_US
dc.description.abstractObjectives: Mad-honey intoxication (MHI) often presents with all kinds of bradyarrhythmias. Despite numerous publications focused on clinical findings, we aim to evaluate poor prognostic implications, ischemia likely electrocardiography (ECG) changes, and detailed ECG findings of MHI in the largest series. Methods: This is a retrospective single-center study of 117 MHI patients admitted to emergency service. Results: The study had 26 (22.2%) females (median 52.5 years) and 91 (77.8%) males (median 51.0 years). Fifty-six (47.9%) patients had ischemia likely changes on ECG. Multivariate model demonstrated that beta-blocker usage (odds ratio (OR): 52.871; 95% confidence interval (CI): 3.618-772.554 (p=0.004)), atrioventricular junctional rhythm (AVJR) (OR: 5.319; 95%CI: 1.090-25.949 (p=0.039)), and quantity of mad-honey consumption (OR: 1.035; 95% CI: 1.008-1.063 (p=0.011)) are predictors of hospitalization. ROC curve analysis showed cutoff value of mad-honey consumption quantity 24.79 g had 57% sensitivity and 68% specificity for predicting hospitalization (AUC: 0.7, 95% CI: 0.55-0.816, p=0.027). In addition, all hospitalized cases were male. Conclusion: Our study has shown that male gender, AVJR, the quantity of mad-honey consumption, and beta-blocker usage are high-risk criteria for hospitalization in MHI patients. Furthermore, ischemia likely ECG changes is often observed with MHI even independently from hypotension or bradycardia.en_US
dc.identifier.doi10.14744/SEMB.2022.45144
dc.identifier.endpage374en_US
dc.identifier.issn1302-7123
dc.identifier.issn1308-5123
dc.identifier.issue3en_US
dc.identifier.pmid36304212en_US
dc.identifier.startpage365en_US
dc.identifier.trdizinid1133945en_US
dc.identifier.urihttps://doi.org/10.14744/SEMB.2022.45144
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1133945
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12464
dc.identifier.volume56en_US
dc.identifier.wosWOS:000906397600010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorKorkut, Semih
dc.institutionauthorŞimşek, Engin Ersin
dc.institutionauthorMayda, Atilla Senih
dc.institutionauthorÖksüz, Şükrü
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofMedical Bulletin of Sisli Etfal Hospitalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectBradycardia; Cardiac Arrhythmias; Cardiotoxicity; Food Poisoning; Honey; Plant Poisoningen_US
dc.subjectLaboratory Findings; Ingestionen_US
dc.titleClinical Presentation, Electrocardiographic Findings, and Factors Related to the Hospitalization In Mad-Honey Intoxicationen_US
dc.typeArticleen_US

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