Carotid intima media thickness and cardiometabolic risk associates in Turkish adults

Basit Öğe Kaydı
dc.contributor.authorBeşir, Fahri Halit
dc.contributor.authorYazgan, Ömer
dc.contributor.authorÖzhan, Hakan
dc.contributor.authorAydın, Yusuf
dc.contributor.authorBaşar, Cengiz
dc.contributor.authorAydın, Mesut
dc.contributor.authorBulur, Serkan
dc.date.accessioned2020-04-30T22:40:33Z
dc.date.available2020-04-30T22:40:33Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000298836300011en_US
dc.descriptionPubMed: 22299387en_US
dc.description.abstractObjective Carotid intima media thickness (CIMT) is a strong predictor of future vascular events. However, data for Turkish individuals are limited and the association between cardiometabolic risk factors and CIMT has not been studied before. Therefore, we sought to investigate the CIMT and cardiometabolic risk associates in a large cohort of Turkish adults. Methods and results The study was conducted on 2230 participants (1427 women, 803 men with a mean age of 49). The participants underwent a Doppler Ultrasound examination of CIMT. Mean CIMT was 0.61 +/- 0.19 mm. Age- and sex-adjusted partial correlation analysis revealed that only systolic blood pressure and smoking amount was significantly correlated with CIMT. Receiver operator characteristics (ROC) calculations showed that age had the best area under the curve (AUC =0.84), smoking had the best sensitivity (86%) and diastolic blood pressure (>88 mmHg) had the best specificity (74%) in predicting a person with thickened carotid intima media (>0.8 mm). Independent predictors of thickened carotid intima media were hypertension [(odds ratio (OR) = 2.74; 95% confidence interval (Cl) = 1.663-4.53; P value <= 0.001)], systolic blood pressure [OR= 1.01; 95% Cl = 1.002-1.022; P value = 0.022] and age [OR= 1.11; 95% Cl = 1.079-1.136; P value <= 0.001). Conclusion Age, systolic blood pressure and smoking amount (pack/year) were the only age- and sex-adjusted associates of CIMT. Age had the best AUC in ROC analysis predicting thickened carotid artery intima media. Hypertension, systolic blood pressure and age were independent predictors of high CIMT in Turkish adults.en_US
dc.identifier.doi10.1080/AC.66.6.2136960en_US
dc.identifier.endpage764en_US
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage759en_US
dc.identifier.urihttps://doi.org/10.1080/AC.66.6.2136960
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3009
dc.identifier.volume66en_US
dc.identifier.wosWOS:000298836300011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarotid intima media thicknessen_US
dc.subjecthypertensionen_US
dc.titleCarotid intima media thickness and cardiometabolic risk associates in Turkish adultsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
3009.pdf
Boyut:
875.31 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu