Could Helium Plasma Treatment be a Novel Approach to Prevent the Biofilm Formation of Candida albicans?

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dc.authoridTopcu Ersöz, Mirac Berke/0000-0003-2953-5255en_US
dc.authoridErdonmez, Demet/0000-0002-5331-2206en_US
dc.authoridAKAY, CANAN/0000-0003-2781-8710en_US
dc.authoridavukat, esra nur/0000-0003-0533-8994en_US
dc.authorscopusid57407449500en_US
dc.authorscopusid56526673700en_US
dc.authorscopusid57445379200en_US
dc.authorscopusid34880569600en_US
dc.authorscopusid9274843500en_US
dc.authorscopusid56049522100en_US
dc.authorwosidTopcu Ersöz, Mirac Berke/IWV-2876-2023en_US
dc.authorwosidAKAY, CANAN/F-8368-2015en_US
dc.contributor.authorAvukat, Esra Nur
dc.contributor.authorAkay, Canan
dc.contributor.authorErsoz, Mirac Berke Topcu
dc.contributor.authorMumcu, Emre
dc.contributor.authorPat, Suat
dc.contributor.authorErdonmez, Demet
dc.date.accessioned2024-08-23T16:07:06Z
dc.date.available2024-08-23T16:07:06Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractThere is no definitive method to prevent Candida albicans (C. albicans) biofilm formation on polymethyl methacrylate (PMMA) surfaces. The objective of this study was to evaluate the effect of Helium plasma treatment (before the application of removable dentures to the patient) to prevent or reduce C. albicans ATCC 10,231 the anti-adherent activity, viability, and biofilm formation on PMMA surfaces. One hundred disc-shaped PMMA samples (2 mm x 10 mm) were prepared. The samples were randomly divided into 5 surface groups and treated with different concentrations of Helium plasma: G I: Control group (untreated), G II: 80% Helium plasma-treated group, G III: 85% Helium plasma-treated group, G IV: 90% Helium plasma-treated group, G V: 100% Helium plasma-treated group. C. albicans viability and biofilm formations were evaluated using 2 methods: MTT (3-(4,5-dimethyl thiazolyl-2)-2, 5-diphenyltetrazolium bromide) assays and Crystal Violet (CV) staining. The surface morphology and C. albicans biofilm images were observed with scanning electron microscopy. The Helium plasma-treated PMMA groups (G II, G III, G IV, G V) observed a significant reduction in C. albicans cell viability and biofilm formation compared with the control group. Treating PMMA surfaces with different concentrations of Helium plasma prevents C. albicans viability and biofilm formation. This study suggests that Helium plasma treatment might be an effective strategy in modifying PMMA surfaces to prevent denture stomatitis formation.en_US
dc.identifier.doi10.1007/s11046-023-00747-9
dc.identifier.endpage369en_US
dc.identifier.issn0301-486X
dc.identifier.issn1573-0832
dc.identifier.issue4en_US
dc.identifier.pmid37294506en_US
dc.identifier.scopus2-s2.0-85161419562en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage361en_US
dc.identifier.urihttps://doi.org/10.1007/s11046-023-00747-9
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14498
dc.identifier.volume188en_US
dc.identifier.wosWOS:001004018800001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofMycopathologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiofilm Formationen_US
dc.subjectCandida albicansen_US
dc.subjectCrystal violeten_US
dc.subjectHelium plasma treatmenten_US
dc.subjectMTTen_US
dc.subjectPMMAen_US
dc.subjectAcrylic Resinen_US
dc.subjectIn-Vitroen_US
dc.subjectSurface Modificationen_US
dc.subjectAdherenceen_US
dc.subjectAdhesionen_US
dc.titleCould Helium Plasma Treatment be a Novel Approach to Prevent the Biofilm Formation of Candida albicans?en_US
dc.typeArticleen_US

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