The predictive role of laboratory parameters in cardiovascular risk assessment in obese

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dc.authoridKaya, Abdulkadir/0000-0003-1725-1220en_US
dc.authorscopusid57349607700en_US
dc.authorscopusid37005547200en_US
dc.authorscopusid58521137400en_US
dc.authorscopusid36468092600en_US
dc.authorwosidKaya, Abdulkadir/JCD-8256-2023en_US
dc.contributor.authorKaya, Abdulkadir
dc.contributor.authorGamsizkan, Zerrin
dc.contributor.authorKaya, Nursel
dc.contributor.authorDavran, Fatih
dc.date.accessioned2024-08-23T16:04:18Z
dc.date.available2024-08-23T16:04:18Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractThe significance of cardiovascular diseases in mortality is indisputable. It is well-established that cardiovascular diseases are more prevalent among individuals with obesity. This study aimed to determine the predictive value of easily accessible hematological and biochemical parameters in assessing cardiovascular risk among obese patients. The study was designed as an observational retrospective. Department of Family Medicine, study was carried out between 25/06/2022 to 30/10/2022. The data of 439 obese patients were analyzed retrospectively. Using the online Heart Score system, the patients were classified into low, medium, high, and very high cardiovascular risk categories. The hemogram and certain biochemistry values of the patients at the time of admission were examined. Receiver operating characteristic (ROC) analyses were conducted to discriminate cardiovascular risk classes based on laboratory values. Markers with high diagnostic value, including a high area under the curve (AUC) value, sensitivity, and specificity, were presented. Significant differences were observed between the groups in terms of age, systolic blood pressure, diastolic blood pressure, total cholesterol, low-density lipoprotein, glucose, HbA1c, hemoglobin, platelet count, neutrophil (NEU) count, and platelet-lymphocyte ratio parameters (P < .05). The white blood cell count and NEU count of patients in the high-risk groups were found to have significantly higher AUC values compared to the moderate-risk group (AUC values of .737 and .779, respectively). The white blood cell and NEU parameters were found to have a positive predictive value in estimating the degree of cardiovascular risk. These parameters can potentially serve as biomarkers in identifying individuals at high risks for cardiovascular diseases.en_US
dc.identifier.doi10.1097/MD.0000000000034634
dc.identifier.issn0025-7974
dc.identifier.issn1536-5964
dc.identifier.issue31en_US
dc.identifier.pmid37543777en_US
dc.identifier.scopus2-s2.0-85166598438en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1097/MD.0000000000034634
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14161
dc.identifier.volume102en_US
dc.identifier.wosWOS:001042802500004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofMedicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcardiovascular risken_US
dc.subjectlaboratory parametersen_US
dc.subjectobesityen_US
dc.subjectHba(1c)en_US
dc.titleThe predictive role of laboratory parameters in cardiovascular risk assessment in obeseen_US
dc.typeArticleen_US

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