Obstructive Sleep Apnea Syndrome, Periodic Limb Movements and Related Factors

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dc.contributor.authorYalın, Osman Özgür
dc.contributor.authorYılmaz, İbrahim Arda
dc.contributor.authorSungur, Mehmet Ali
dc.contributor.authorDoğu, Okan
dc.date.accessioned2020-04-30T23:19:48Z
dc.date.available2020-04-30T23:19:48Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000372008100003en_US
dc.description.abstractObjective: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive nocturnal apnea episodes. Periodic limb movements (PLMs) is known as the nocturnal, stereotypic, repetitive movements of the lower extremities. The aim of this study was to investigate the presence of PLMs in patients with OSAS, and the relationship between PLM and OSAS severity. Materials and Methods: One hundred forty-one patients who had a pre-diagnosis of OSAS were enrolled into the study. All subjects' blood pressure, heart rate measurements, and neurologic examinations were performed by the same neurologist. Sociodemographic characteristics were recorded. Overnight polysomnography (PSG) was performed in all patients and results were analyzed. Patients with an apnea-hypopnea index (AHI) of >= 5 were accepted as having OSAS, and a PLM index (PLMI) of >= 5 were accepted as having PLM. Results: One hundred two patients were diagnosed as having OSAS. The control group consisted of 39 patients who had normal polysomnographic findings. The patients with OSAS were older and their body mass indexes (BMI) were higher compared with the control group. Systolic blood pressure was higher in the OSAS group. Alcohol use was found to be a risk factor for OSAS. PLM was more common in the OSAS group than in the control group (30.3-10.2%). PLM frequency was associated with the severity of OSAS. Conclusion: The presence of PLM was associated with OSAS severity, higher systolic and diastolic blood pressure, and REM sleep depletion in OSAS. PLM seen in patients with OSAS may be regarded as an indicator of disease severity, and should alert the physician to increased complications.en_US
dc.identifier.doi10.4274/tnd.25993en_US
dc.identifier.endpage94en_US
dc.identifier.issn1301-062X
dc.identifier.issn1309-2545
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage90en_US
dc.identifier.urihttps://doi.org/10.4274/tnd.25993
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3857
dc.identifier.volume21en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkish Neurological Socen_US
dc.relation.ispartofTurkish Journal Of Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectObstructive sleep apnea syndromeen_US
dc.subjectperiodic limb movementsen_US
dc.subjectpolysomnographyen_US
dc.titleObstructive Sleep Apnea Syndrome, Periodic Limb Movements and Related Factorsen_US
dc.typeArticleen_US

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