Evaluation of Bone Mineral Density and Bone Turnover Markers in Patients with non-Cirrhotic Chronic Hepatitis B

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dc.contributor.authorÇelebi, Güven
dc.contributor.authorSarıkaya, Selda
dc.contributor.authorÖzdolap, Şenay
dc.contributor.authorMungan, Görkem
dc.contributor.authorAnkaralı, Handan
dc.contributor.authorÇelik, Yavuz
dc.contributor.authorAkduman, Deniz
dc.date.accessioned2020-05-01T12:11:57Z
dc.date.available2020-05-01T12:11:57Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionAnkarali, Handan Camdeviren/0000-0002-3613-0523en_US
dc.descriptionWOS: 000305320400004en_US
dc.description.abstractObjective: To evaluate the bone mineral density (BMD) and the biochemical markers of bone turnover in non-cirrhotic chronic hepatitis B patients. Material and Methods: We compared 18-65 years old non-cirrhotic chronic hepatitis B patients and healthy controls for BMD and biochemical markers of bone turnover. BMD was measured at the lumbar spine and the left hip using DXA. Results: There were 31 hepatitis B patients (19 males, 12 females) and 72 healthy controls (56 males, 16 females) in the study. Their mean age was 37.4 +/- 10.0 years in the study group and 38.5 +/- 7.1 years in the controls. There were no differences between the two groups for the mean BMD levels and T scores. However, left hip BMD and T scores were significantly lower in male patients with chronic hepatitis B infection when compared to males in the control group. Serum calcium, phosphate, osteocalcine, intact parathyroid hormone, deoxypyridinoline and 25-hydroxycholecalciferol levels did not differ between the groups. Conclusion: In our study, left hip BMD and T scores were found to be significantly lower in the male patients with chronic hepatitis B infection when compared to males in the control group, however a significant difference was not detected when all cases were compared with the control group. Therefore, we suppose that further studies on a larger population are needed in this issue.en_US
dc.identifier.doi10.5336/medsci.2011-22718en_US
dc.identifier.endpage330en_US
dc.identifier.issn1300-0292
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage324en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2011-22718
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6299
dc.identifier.volume32en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherOrtadogu Ad Pres & Publ Coen_US
dc.relation.ispartofTurkiye Klinikleri Tip Bilimleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHepatitis B virusen_US
dc.subjectchronic hepatitis Ben_US
dc.subjectbone densityen_US
dc.titleEvaluation of Bone Mineral Density and Bone Turnover Markers in Patients with non-Cirrhotic Chronic Hepatitis Ben_US
dc.typeArticleen_US

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