Are the conventional risk factors still valid for acute myeloid leukemia patients?

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dc.contributor.authorYıldız, Abdulkerim
dc.contributor.authorMaral, Senem
dc.contributor.authorAlbayrak, Murat
dc.contributor.authorPala, Çiğdem
dc.contributor.authorCömert, Pınar
dc.contributor.authorAfacan Öztürk, Hacer Berna
dc.contributor.authorŞahin, Osman
dc.date.accessioned2024-12-28T20:28:42Z
dc.date.available2024-12-28T20:28:42Z
dc.date.issued2020
dc.description.abstractObjective: Theaim of this study was to investigate the survival data of patients with acutemyeloid leukemia (AML) and to determine the risk factors that can be easily evaluated.Method: Aretrospective analysis  was made of the AML patients admitted to our center between2009-2018. Demographic data and disease data were analyzed and response rates,overall survival (OS) and progression-free survival (PFS) rates werecalculated. Factors affecting survival were determined using Cox-regressionanalysis.Results: Atotal of 119 patients were included in the study during the 9-year studyperiod. Of these, 21 patients had secondary AML and 11 had acute promyelocyticleukemia (APL). The mean follow-up period was 12.43 ± 15.63 months. OS of allpatients was 9.20 months and PFS was 7.23 months. Age and leukocyte count atthe time of diagnosis were found to have a significant impact on both OS andPFS (p lt;0.05).Conclusion:In addition to genetic and molecular features, which are expensive and noteasily available, the age and leukocyte count of AML patients remain important asprognostic factors.
dc.identifier.dergiparkDergiPark: 549666
dc.identifier.doi10.18521/ktd.549666
dc.identifier.endpage11
dc.identifier.issn1309-3878
dc.identifier.issn1309-3878
dc.identifier.issue1
dc.identifier.startpage5
dc.identifier.urihttps://doi.org/10.18521/ktd.549666
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/990065
dc.identifier.urihttps://dergipark.org.tr/tr/pub/ktd/issue/52800/549666
dc.identifier.urihttps://hdl.handle.net/20.500.12684/17857
dc.identifier.volume12
dc.language.isoen
dc.publisherDüzce Üniversitesi
dc.relation.ispartofKonuralp Medical Journal
dc.relation.ispartofKonuralp Tip Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241228
dc.subjectleukemia
dc.subjectsurvival
dc.subjectage
dc.subjectHealth Care Administration
dc.titleAre the conventional risk factors still valid for acute myeloid leukemia patients?
dc.typeArticle

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