Are the conventional risk factors still valid for acute myeloid leukemia patients?
Yükleniyor...
Dosyalar
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Düzce Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Theaim of this study was to investigate the survival data of patients with acutemyeloid leukemia (AML) and to determine the risk factors that can be easily evaluated.Method: Aretrospective analysis was made of the AML patients admitted to our center between2009-2018. Demographic data and disease data were analyzed and response rates,overall survival (OS) and progression-free survival (PFS) rates werecalculated. Factors affecting survival were determined using Cox-regressionanalysis.Results: Atotal of 119 patients were included in the study during the 9-year studyperiod. Of these, 21 patients had secondary AML and 11 had acute promyelocyticleukemia (APL). The mean follow-up period was 12.43 ± 15.63 months. OS of allpatients was 9.20 months and PFS was 7.23 months. Age and leukocyte count atthe time of diagnosis were found to have a significant impact on both OS andPFS (p lt;0.05).Conclusion:In addition to genetic and molecular features, which are expensive and noteasily available, the age and leukocyte count of AML patients remain important asprognostic factors.
Açıklama
Anahtar Kelimeler
leukemia, survival, age, Health Care Administration
Kaynak
Konuralp Medical Journal
Konuralp Tip Dergisi
Konuralp Tip Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
12
Sayı
1
