Evaluation of carotid intima media thickness in impaired fasting glucose and impaired glucose tolerance

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dc.contributor.authorAydın, Yusuf
dc.contributor.authorBerker, Dilek
dc.contributor.authorÜstün, İhsan
dc.contributor.authorGül, Kamile
dc.contributor.authorErden, Gönül
dc.contributor.authorKutlucan, Ali
dc.contributor.authorGüler, Serdar
dc.date.accessioned2020-05-01T12:11:57Z
dc.date.available2020-05-01T12:11:57Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionUstun, Ihsan/0000-0002-5848-1586en_US
dc.descriptionWOS: 000296755600003en_US
dc.descriptionPubMed: 22019748en_US
dc.description.abstractAim. Increased carotid intima media thickness (CIMT) is recognized as the early indicator of atherosclerosis. We aimed to evaluate the effect of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) on the CIMT. Methods. We evaluated 51 dysglycemic patients (IFG [N.=22]; IGT [N.=29]) and 25 controls who have similar age and gender. Patients who were known to have coronary heart disease, cerebrovascular disease, hypertension, hyperlipidemia, diabetes mellitus and hypo-hyperthyrodism were excluded. We measured fasting blood glucose (FBG), postprandial blood glucose (PPG), insulin, insulin resistance, lipid profile, hsCRP, microalbuminuria, and glycosylated hemoglobin A1c (HbA1c). We measured the CIMT by Doppler ultrasonography. Results. Both IFG and IGT patients have increased CIMT according to controls (P<0.001). Mean CIMT of IFG, IGT and control were 0.704, 0.738 and 0.555 respectively. There were no differences in point of fasting insulin and HOMA-IR between IFG and IGT. There were positive correlation of CIMT and FBG, PPG, HbA1c, fasting insulin and HOMA-IR in both groups. In linear regression analysis, PPG and HbA1c is the major factor affecting CIMT (t=0.017 and 0.036). Conclusion. IFG and IGT have increased CIMT according to controls, and PPG and HbA1c are the major affecting factors to CIMT.en_US
dc.identifier.endpage179en_US
dc.identifier.issn0391-1977
dc.identifier.issn1827-1634
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage171en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6300
dc.identifier.volume36en_US
dc.identifier.wosWOS:000296755600003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofMinerva Endocrinologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlucose toleranceen_US
dc.subjectAtherosclerosisen_US
dc.subjectCarotid stenosisen_US
dc.titleEvaluation of carotid intima media thickness in impaired fasting glucose and impaired glucose toleranceen_US
dc.typeArticleen_US

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