First episode psychosis: The relation between symptoms, initial treatment, and clinical response

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dc.contributor.authorYıldızhan, Eren
dc.contributor.authorTürkcan, Ahmet
dc.contributor.authorİnan, Serhat
dc.contributor.authorErenkuş, Zehra
dc.contributor.authorYalçın, Özhan
dc.contributor.authorErdoğan, Ayten
dc.date.accessioned2020-04-30T13:32:30Z
dc.date.available2020-04-30T13:32:30Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionPubMed ID: 26111283en_US
dc.description.abstractObjective: It was aimed to explore the relationship of clinical psychopathology and treatment response with "duration of untreated psychosis" (DUP) and "duration of untreated illness"(DUI) in 15-20 years old (mean age: 17,34 ± 1.69) inpatients in Turkey. Method: Mood disorders with psyhotic features were grouped as affective psychoses (18 patients, mean age: 17,28 ± 1,75); schizophrenia, schizophreniform disorder and other psychotic disorders were grouped as non-affective psychoses (25 patients, mean age: 17,38 ± 1,68). 43 patiens (11 females, 32 males) were evaluated for acute treatment response with Positive and Negative Sydrome Scale - PANSS and Clinical Global Impressions Scale -CGI. Results: Mean DUP was determined as 6,5 ± 12,4 weeks, mean DUI was determined as 37,8 ± 49,8 weeks. For the affective psychosis (AP) group; mean DUP was 1,9 ± 1,2 weeks, mean DUI was 24,6 ± 37,1 weeks, for the non-affective psychosis (NAP) group; mean DUP was 9,8 ± 15,5 weeks, mean DUI was 47,3 ± 55,9 weeks. Treatment response was better for the non-affective psychosis group and for the patients who had earlier access to treatment. Shorter DUP and DUI was related with better PANSS negative symptom severity at the time of the discharge. Conclusion: Better treatment response related with shorter DUP and DUI reveals the significance of early treatment for the disease prognosis.en_US
dc.identifier.doi10.5080/u7818en_US
dc.identifier.endpage86en_US
dc.identifier.issn1300-2163
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage77en_US
dc.identifier.urihttps://dx.doi.org/10.5080/u7818
dc.identifier.urihttps://hdl.handle.net/20.500.12684/321
dc.identifier.volume26en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Association of Nervous and Mental Healthen_US
dc.relation.ispartofTurk Psikiyatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdolescent psychiatry; Age of onset; Prodromal symptoms; Psychopharmacology; Psychotic disordersen_US
dc.titleFirst episode psychosis: The relation between symptoms, initial treatment, and clinical responseen_US
dc.typeArticleen_US

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